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Stereotaktische Strahlentherapie übertrifft Sorafenib beim fortgeschrittenen hepatozellulären Karzinom im Hinblick auf das Überleben

Stereotactic body radiation therapy is superior to sorafenib in terms of survival in patients with hepatocellular carcinoma

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Literatur

  1. Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc J‑F et al (2008) Sorafenib in advanced hepatocellularcarcinoma. N Engl J Med 359:378–390

    Article  CAS  PubMed  Google Scholar 

  2. Forner A, Llovet JM, Bruix J (2012) Hepatocellular carcinoma. Lancet 379:1245–1255

    Article  PubMed  Google Scholar 

  3. Llovet JM, Ducreux M, Lencioni R, Di Bisceglie AM, Galle PR, Dufour JF et al (2012) EASL-EORTC clinical practiceguidelines: management of hepatocellular carcinoma. J Hepatol 56:908–943

    Article  Google Scholar 

  4. Bujold A, Massey CA, Kim JJ, Brierley J, Cho C, Wong RKS et al (2013) Sequential phase I and II trials of stereotacticbody radiotherapy for locally advanced hepatocellular carcinoma. J ClinOncol 31:1631–1639

    Article  Google Scholar 

  5. Qiu H, Moravan MJ, Milano MT, Usuki KY, Katz AW (2018) SBRT for hepatocellular carcinoma: 8‑year experience froma regional transplant center. J Gastrointest Cancer. https://doi.org/10.1007/s12029-017-9990-1

    Article  PubMed  Google Scholar 

  6. Wahl DR, Stenmark MH, Tao Y, Pollom EL, Caoili EM, Lawrence TS et al (2016) Outcomes after stereotactic body radiotherapy or radiofrequency ablation for hepatocellular carcinoma. J Clin Oncol 34:452–459

    Article  CAS  PubMed  Google Scholar 

  7. Sapir E, Tao Y, Schipper MJ, Bazzi L, Novelli PM, Devlin P et al (2018) Stereotactic body radiation therapy as an alternative to transarterial chemoembolization for hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 100:122–130

    Article  PubMed  Google Scholar 

  8. Vilgrain V, Pereira H, Assenat E, Guiu B, Ilonca AD, Pageaux GP et al (2017) Efficacy and safety of selective internal radiotherapy with yttrium-90 res in microspheres compared with sorafenib in locally advanced and inoperablehepatocellular carcinoma (SARAH): an open-label randomised controlled phase 3 trial. Lancet Oncol 18:1624–1636

    Article  CAS  PubMed  Google Scholar 

  9. Gandhi M, Choo SP, Thng CH, Tan SB, Low ASC, Cheow PC et al (2016) Single administration of Selective InternalRadiation Therapy versus continuous treatment with sorafeNIB in locally advanced hepatocellular carcinoma(SIRveNIB): study protocol for a phase III randomized controlled trial. BMC Cancer 16:856

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Universitätsklinik für Medizinische Strahlenphysik, Medizinischer Campus Pius-Hospital, Carl von Ossietzky Universität Oldenburg, Oldenburg, Deutschland

    Ping Jiang

  2. Klinik für Strahlentherapie, Universitätsklinikum Schleswig-Holstein, Kiel, Deutschland

    Jürgen Dunst

Authors
  1. Ping Jiang
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  2. Jürgen Dunst
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Correspondence to Ping Jiang or Jürgen Dunst.

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P. Jiang und J. Dunst geben an, dass kein Interessenkonflikt besteht.

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Originalpublikation

Bettinger D, Pinato DJ, Schultheiss M et al (2018) Stereotactic body radiation therapy as an alternative treatment for patients with hepatocellular carcinoma compared to Sorafenib: a propensity score analysis. Liver Cancer, Published online: July 12, 2018. https://doi.org/10.1159/000490260

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Jiang, P., Dunst, J. Stereotaktische Strahlentherapie übertrifft Sorafenib beim fortgeschrittenen hepatozellulären Karzinom im Hinblick auf das Überleben. Strahlenther Onkol 195, 188–189 (2019). https://doi.org/10.1007/s00066-018-1408-x

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