Skip to main content
SpringerLink
Log in

Langzeitergebnisse der adjuvanten im Vergleich zur Early-Salvage-Bestrahlung beim pT3N0-Prostatakarzinom nach radikaler Prostatektomie

Long-term results of adjuvant versus early salvage radiation therapy in pT3N0 prostate cancer after radical prostatectomy

  • Literatur kommentiert
  • Published:
Strahlentherapie und Onkologie Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Bolla M, Van Poppel H, Tombal B et al (2012) Postoperative radiotherapy after radical prostatectomy for high-risk prostate cancer: long-term results of a randomised controlled trial (EORTC trial 22911). Lancet 380:2018–2027

    Article  PubMed  Google Scholar 

  2. Wiegel T, Bartkowiak D, Bottke D et al (2014) Adjuvant radiotherapy versus wait-and-see after radical prostatectomy: 10-year follow-up of the ARO 96-02/AUO AP 09/95 trial. Eur Urol 66:243–250

    Article  PubMed  Google Scholar 

  3. Thompson IM, Tangen CM, Paradelo J et al (2009) Adjuvant radiotherapy for pathological T3N0M0 prostate cancer significantly reduces risk of metastases and improves survival: long-term followup of a randomized clinical trial. J Urol 181:956–962

    Article  PubMed  PubMed Central  Google Scholar 

  4. Zakeri K, Rose BS, Gulaya S et al (2013) Competing event risk stratification may improve the design and efficiency of clinical trials: secondary analysis of SWOG 8794. Contemp Clin Trials 34:74–79

    Article  PubMed  Google Scholar 

  5. Interdisziplinäre Leitlinie der Qualität S3 zur Früherkennung, Diagnose und Therapie der verschiedenen Stadien des Prostatakarzinoms. Langversion 4.0 – Dezember 2016. AWMF-Register-Nummer 043/022OL http://leitlinienprogramm-onkologie.de/index.php?id=58&type=0. Zugegriffen: 12.12.2017

  6. King CR (2012) The timing of salvage radiotherapy after radical prostatectomy: a systematic review. Int J Radiat Oncol Biol Phys 84:104–111

    Article  PubMed  Google Scholar 

  7. Ohri N, Dicker AP, Trabulsi EJ et al (2012) Can early implementation of salvage radiotherapy for prostate cancer improve the therapeutic ratio? A systematic review and regression meta-analysis with radiobiological modelling. Eur J Cancer 48:837–844

    Article  PubMed  Google Scholar 

  8. Kang JJ, Reiter RE, Steinberg ML et al (2015) Ultrasensitive prostate specific antigen after prostatectomy reliably identifies patients requiring postoperative radiotherapy. J Urol 193:1532–1538

    Article  PubMed  Google Scholar 

  9. Budäus L, Schiffmann J, Graefen M, Huland H, Tennstedt P, Siegmann A, Böhmer D, Budach V, Bartkowiak D, Wiegel T (2017) Defining biochemical recurrence after radical prostatectomy and timing of early salvage radiotherapy: informing the debate. Strahlenther Onkol. https://doi.org/10.1007/s00066-017-1140-y

    PubMed  Google Scholar 

  10. Briganti A, Wiegel T, Joniau S et al (2012) Early salvage radiation therapy does not compromise cancer control in patients with pT3N0 prostatecancer after radical prostatectomy: results of a match-controlledmulti-institutional analysis. Eur Urol 62:472–487

    Article  PubMed  Google Scholar 

  11. U.S. National Library of Medicine (2009) clinical trails.gov. TROG 08.03 RAVES: https://clinicaltrials.gov/ct2/show/NCT00860652. Zugegriffen: 12.12.2017

  12. U.S. National Library of Medicine (2007) clinical trails.gov. RADICALS: https://clinicaltrials.gov/ct2/show/NCT00541047. Zugegriffen: 12.12.2017

  13. U.S. National Library of Medicine (2008) clinical trails.gov. GETUG-17: https://clinicaltrials.gov/ct2/show/NCT00667069. Zugegriffen: 12.12.2017

  14. U.S. National Library of Medicine (2017) clinical trails.gov. EORTC 22043-30041: https://clinicaltrials.gov/ct2/show/NCT00949962. Zugegriffen: 12.12.2017

Download references

Author information

Authors and Affiliations

  1. Zentrum für Strahlentherapie, Mozartstr. 30, 26655, Westerstede, Deutschland

    R. M. Hermann

  2. Klinik für Strahlentherapie und Spezielle Onkologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland

    H. Christiansen

Authors
  1. R. M. Hermann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Christiansen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to R. M. Hermann.

Ethics declarations

Interessenkonflikt

R. M. Hermann und H. Christiansen geben an, dass kein Interessenkonflikt besteht.

Additional information

Originalpublikation

Fossati N, Karnes RJ, Boorjian SA et al (2017) Long-term impact of adjuvant versus early salvage radiation therapy in pT3N0 prostate cancer patients treated with radical prostatectomy: results from a multi-institutional series. Eur Urol 71:886–893

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hermann, R.M., Christiansen, H. Langzeitergebnisse der adjuvanten im Vergleich zur Early-Salvage-Bestrahlung beim pT3N0-Prostatakarzinom nach radikaler Prostatektomie . Strahlenther Onkol 194, 181–184 (2018). https://doi.org/10.1007/s00066-017-1242-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00066-017-1242-6

Search

Navigation