Strahlentherapie und Onkologie

, Volume 190, Issue 5, pp 467–471 | Cite as

Using fiducial markers in the prostate bed in postprostatectomy external beam radiation therapy improves accuracy over surgical clips

  • I. Fortin
  • J.-F. Carrier
  • M.-C. Beauchemin
  • D. Béliveau-Nadeau
  • G. Delouya
  • D. TausskyEmail author
Original article


Background and purpose

The purpose of this work was to assess the stability of fiducial markers in the prostate bed and compared their use to surgical clips.

Patients and methods

In this study, 3–4 gold fiducial markers were transrectally implanted in the prostate bed of 14 patients. The stability of the fiducial markers position (fiducial markers fixity) over an EBRT course was assessed. Furthermore, the advantages of the fiducial markers compared to the surgical clips were assessed and the interobserver variation between the two technologies was compared.


The mean fiducial marker migration during a course of EBRT was small with 1.2 mm (SD ± 0.8 mm). Compared to fiducial markers, the matches with surgical clips were mismatched ≥ 2 mm in 68 % of treatments. This discrepancy of > 2 mm was on average 3.7 ± 1.3 mm. There was less interobserver variability for matching of fiducial markers (0.8 ± 0.7 mm) than for surgical clips (2.0 ± 1.6 mm).


Fiducial markers showed less interobserver variability in matching and less variation in position than surgical clips. Fiducial markers could ultimately help in reducing treatment margins.


Toxicity Organs at risk Treatment margins Reference standards Radiotherapy, image-guided 

Goldmarker im Prostatabett bei der Strahlenbehandlung nach Prostatektomie: erhöhte Genauigkeit im Vergleich zu Operationsklammern


Hintergrund und Ziel

Es wurde die Stabilität von Goldmarkern im Prostatabett untersucht und ihr Nutzen mit dem von Operationsklammern verglichen.

Patienten und Methoden

Bei 14 untersuchten Patienten wurden 3–4 Goldmarker transrektal in das Prostatabett eingesetzt. Während der Bestrahlung wurde die Stabilität der Position der Marker gemessen. Ferner wurden die Vorteile der Goldmarker mit denen der Operationsklammern sowie die Interbeobachtervariation bei beiden verglichen.


Die Migration der Goldmarker im Prostatabett war während der Bestrahlung mit einem Durschnitt von 1,2 mm (Standardabweichung ± 0,8 mm) klein. Wenn man das „matching“ von Operationsklammern mit dem „matching“ von Goldmarkern vergleicht, so gab es in 68 % der Bestrahlungen eine Diskrepanz von > 2 mm (durchschnittlich 3,7 ± 1,3 mm). Die Interbeobachtervariation war für den Gebrauch von Goldmarkern (0,8 ± 0,7 mm) im Vergleich zu Operationsklammern (2,0 ± 1,6 mm) geringer.


Goldmarker waren zuverlässiger als Operationsklammern, da sie eine kleinere Variabilität beim „matching“ zeigten. Nach Ansicht der Autoren können Goldmarker helfen, den Sicherheitsrand zu verringern.


Toxizität Gefährdete Organe Bestrahlungsfeld Referenzstandards Bildgestützte Radiotherapie 



We thank Genevieve Robitaille and Sara Dufort-Venne for their work and Dr. David Roberge for help with the preparation of the manuscript

Compliance with ethicalguidelines

Conflict of interest

I. Fortin, J. F. Carrier, M. C. Beauchemin, D. Béliveau-Nadeau, G. Delouya, and D. Taussky state that there are no conflicts of interest.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • I. Fortin
    • 1
  • J.-F. Carrier
    • 1
  • M.-C. Beauchemin
    • 1
  • D. Béliveau-Nadeau
    • 1
  • G. Delouya
    • 1
  • D. Taussky
    • 1
    Email author
  1. 1.Département de Radio-OncologieCentre Hospitalier de l’Université de Montréal, Centre de recherche du Centre Hospitalier de l’Université de Montréal, Hôpital Notre-DameMontréalCanada

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