Literatur
Grainger DJ, Heathcote K, Chiano M et al (1999) Genetic control of the circulating concentration of transforming growth factor type beta1. Hum Mol Genet 8:93–97
Guerra JL, Gomez D, Wei Q et al (2012) Association between single nucleotide polymorphisms of the transforming growth factor beta1 gene and the risk of severe radiation esophagitis in patients with lung cancer. Radiother Oncol 105:299–304
Jin H, Tucker SL, Liu HH et al (2009) Dose-volume thresholds and smoking status for the risk of treatment-related pneumonitis in inoperable non-small cell lung cancer treated with definitive radiotherapy. Radiother Oncol 91:427–432
Niu X, Li H, Chen Z et al (2012) A study of ethnic differences in TGFbeta1 gene polymorphisms and effects on the risk of radiation pneumonitis in non-small-cell lung cancer. J Thorac Oncol 7:1668–1675
Raabe A, Derda K, Reuther S et al (2012) Association of single nucleotide polymorphisms in the genes ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with risk of severe erythema after breast conserving radiotherapy. Radiat Oncol 7:65
Reuther S, Metzke E, Bonin M et al (2013) No effect of the transforming growth factor beta1 promoter polymorphism C-509T on TGFB1 gene expression, protein secretion, or cellular radiosensitivity. Int J Radiat Oncol Biol Phys 85:460–465
Yuan X, Liao Z, Liu Z et al (2009) Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk of radiation pneumonitis in patients with non-small-cell lung cancer treated with definitive radiotherapy. J Clin Oncol 27:3370–3378
Zhang L, Yang M, Bi N et al (2010) Association of TGF-beta1 and XPD polymorphisms with severe acute radiation-induced esophageal toxicity in locally advanced lung cancer patients treated with radiotherapy. Radiother Oncol 97:19–25
Einhaltung der ethischen Richtlinien
Interessenkonflikt. E. Dikomey, S. Reuther und U. Höller geben an, dass kein Interessenkonflikt besteht.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Dikomey, E. Prädiktive Marker für die akute Normalgewebetoxizität bei Bestrahlung von nicht-kleinzelligen Lungenkarzinomen. Strahlenther Onkol 189, 806–808 (2013). https://doi.org/10.1007/s00066-013-0399-x
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00066-013-0399-x