Akutes Leberversagen

  • K. Rutter
  • T. Horvatits
  • A. Drolz
  • K. Roedl
  • S. Siedler
  • S. Kluge
  • V. Fuhrmann
Übersichten

Zusammenfassung

Das akute Leberversagen (ALV) ist ein seltenes, aber lebensbedrohliches Zustandsbild. Charakteristisch ist das rasche Auftreten eines schweren Leberschadens mit hepatozellulärer Nekrose und eingeschränkter Leberfunktion. Bei weiterhin hoher Mortalität ist ein frühzeitiges Erkennen und Einleiten einer ursachenspezifischen unterstützenden sowie v. a. intensivmedizinischen symptomatischen Therapie essenziell. Durch Fortschritte im Bereich der intensivmedizinischen Behandlung von Patienten mit akutem Leberversagen sowie der Lebertransplantation konnte das Überleben deutlich verbessert werden.

Schlüsselwörter

Akutes Leberversagen ALV Intensivmedizin 

Acute liver failure

Abstract

Acute liver failure (ALF) is a rare condition with fatal outcome. Characteristic is rapid onset of liver damage without preexisting liver diseases, including hepatic encephalopathy and coagulopathy. Early and correct diagnosis is essential for further management of patients, since diagnosis impacts therapy choice. Survival of patients with ALF has improved dramatically due to advances in critical care medicine and the use of liver transplantation.

Keywords

Acute liver failure ALF Critical care medicine 

Notes

Einhaltung ethischer Richtlinien

Interessenkonflikt

K. Rutter, T. Horvatits, A. Drolz, K. Roedl, S. Siedler, S. Kluge und V. Fuhrmann geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • K. Rutter
    • 1
  • T. Horvatits
    • 1
  • A. Drolz
    • 1
  • K. Roedl
    • 1
  • S. Siedler
    • 1
  • S. Kluge
    • 1
  • V. Fuhrmann
    • 1
  1. 1.Klinik für IntensivmedizinUniversitätsklinikum Hamburg-EppendorfHamburgDeutschland

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