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Phenobarbitalintoxikation in suizidaler Absicht

Kontinuierliche venovenöse Hämodialyse als effektive Therapie

Suicide attempt by means of phenobarbital overdose

Effective treatment with continuous veno-venous hemodialysis

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Zusammenfassung

Eine 68-jährige Patientin führte mithilfe von Phenobarbitaltabletten, die für ihren epilepsiekranken Hund vorgesehen waren, einen Suizidversuch durch. Zum Aufnahmezeitpunkt war die Patientin bewusstlos und wurde beatmet. Eine 5-tägige konservative intensivmedizinische Therapie führte zu keiner Verbesserung der Vigilanz. Durch eine kontinuierliche venovenöse Hämodialyse konnte eine im Vergleich zur endogenen Ausscheidung 5-fach schnellere Reduktion der Phenobarbitalkonzentration erreicht werden. Die Patientin überlebte unbeschadet. Eine dezidierte Anamnese und die rechtzeitige Indikationsstellung zur Dialyse waren entscheidend.

Abstract

A 68-year-old woman tried to commit suicide using phenobarbital, which was initially prescribed for her dog that suffered from seizures. At admission she was unconscious and ventilated. Five days of intensive care therapy did not improve her state of consciousness. Subsequent continuous veno-venous hemodialysis accelerated the elimination of phenobarbital compared to endogenous elimination by a factor of five. The patient survived without sequelae. Detailed history taking and well-timed indication for dialysis were crucial.

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Authors and Affiliations

  1. Medizinische Klinik I, Klinikum Herford, Schwarzenmoorstraße 70, 32049, Herford, Deutschland

    M. Ruhe &  T. Pohle

  2. Medizinische Klinik III, Klinikum Herford, Schwarzenmoorstraße 70, 32049, Herford, Deutschland

    S. Grautoff &  J. Kähler

Authors
  1. M. Ruhe
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  2. S. Grautoff
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  3. J. Kähler
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  4. T. Pohle
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Correspondence to M. Ruhe.

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M. Ruhe, T. Pohle, S. Grautoff und J. Kähler geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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R. Riessen

Tübingen

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Ruhe, M., Grautoff, S., Kähler, J. et al. Phenobarbitalintoxikation in suizidaler Absicht. Med Klin Intensivmed Notfmed 111, 141–144 (2016). https://doi.org/10.1007/s00063-015-0046-7

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  • DOI: https://doi.org/10.1007/s00063-015-0046-7

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