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Low Dose Pediatric CT Head Protocol using Iterative Reconstruction Techniques: A Comparison with Standard Dose Protocol

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Abstract

Purpose

Pediatric computed tomography (CT) head examination has also increased in recent years with the advancement in CT technology; however, children exposed to radiation at the youngest age are more vulnerable to the risks of radiation. The aim of the study is to evaluate radiation dose and image quality of low dose pediatric CT head protocol compared to standard dose pediatric CT head protocol.

Methods

This was a prospective study. Group 1 included 73 patients aged < 1 year and 70 patients in the 1–5 years age group and had undergone CT head examination using the standard dose protocol. Group 2 included 31 patients aged < 1 year and 40 patients in the 1–5 years age group and had undergone CT head examination using the low dose protocol. The radiation dose was measured and image quality was assessed quantitatively and qualitatively.

Results

There was a significant difference in radiation dose between the standard and low dose protocols (p > 0.05) with lower radiation dose for low dose group. The qualitative analysis did not show a significant difference between the standard and low dose protocols. The gray-white matter differentiation (GWMD), attenuation, contrast to noise ratio (CNR) and figure of merit (FOM) were higher in the low dose protocol compared to the standard dose with a significant difference (p > 0.05).

Conclusion

The study concludes that a low dose protocol at 80 kV tube voltage/150 mAs tube current exposure time product/iterative reconstruction-iDose4 (level 3) for < 1 year age group and 100 kV/200m As/iDose4 (level 3) for 1–5 years age group provides ultra-low effective dose with diagnostically acceptable image quality for pediatric CT head examination compared with standard dose protocol.

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Authors and Affiliations

Authors

Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by all authors. The first draft of the manuscript was written by Dr. Priyanka and all authors commented on the first draft of the manuscript. Statistical analysis: Dr. Priyanka and Dr. Rajagopal Kadavigere, supervision: Dr. Rajagopal Kadavigere and Dr. Suresh Sukumar. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Rajagopal Kadavigere.

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Conflict of interest

Priyanka, R. Kadavigere and S. Sukumar declare that they have no competing interests.

Ethical standards

The current study was approved by the Institutional Ethics Committee of the Kasturba Medical College and Kasturba Hospital, Manipal (IEC:610/2018). All procedures performed in studies involving human participants or on human tissue were in accordance with the ethical standards of the institutional and/or national research committee and with the 1975 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained prior to the participation in the study from the legal guardians of the participants.

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Priyanka, Kadavigere, R. & Sukumar, S. Low Dose Pediatric CT Head Protocol using Iterative Reconstruction Techniques: A Comparison with Standard Dose Protocol. Clin Neuroradiol 34, 229–239 (2024). https://doi.org/10.1007/s00062-023-01361-4

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