Skip to main content
SpringerLink
Log in

Signal Abnormalities in Noonan Syndrome are Probably Consistent with Focal Areas of Signal Intensity (FASI)

  • Correspondence
  • Published:
Clinical Neuroradiology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. D’Amico A, Cipullo MB, Falco M, Ugga L, Melis D. Clinical report of a brain magnetic resonance imaging finding in Noonan syndrome. Childs Nerv Syst. 2021;37(12):3963–6. https://doi.org/10.1007/s00381-021-05149-0.

    Article  PubMed  Google Scholar 

  2. Kang M, Lee YS. The impact of RASopathy-associated mutations on CNS development in mice and humans. Mol Brain. 2019;12:96. https://doi.org/10.1186/s13041-019-0517-5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Salman MS, Hossain S, Alqublan L, Bunge M, Rozovsky K. Cerebellar radiological abnormalities in children with neurofibromatosis type 1: part 1—clinical and neuroimaging findings. Cerebellum Ataxias. 2018;5:14. https://doi.org/10.1186/s40673-018-0093-y

  4. Salman MS, Hossain S, Gorun S, Alqublan L, Bunge M, Rozovsky K. Cerebellar radiological abnormalities in children with neurofibromatosis type 1: part 2—a neuroimaging natural history study with clinical correlations. Cerebellum Ataxias. 2018;5:13. https://doi.org/10.1186/s40673-018-0092-z

  5. de Jong M, Schieving J, Goraj B. Remarkable intra-cerebral lesions on MRI in a patient with Noonan syndrome. Eur J Radiol Extra. 2011;78:17–9. https://doi.org/10.1016/j.ejrex.2011.01.005.

    Article  Google Scholar 

Download references

Funding

No funding was received for this study.

Author information

Authors and Affiliations

  1. Department of Radiology, AZ Maria Middelares, Buitenring Sint-Denijs 30, 9000, Ghent, Belgium

    Arne Vermeulen

  2. Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK

    Felice D’Arco

  3. Department of Neurology, AZ Maria Middelares, 9000, Ghent, Belgium

    Liesbeth De Groote

  4. Department of Radiology, AZ Maria Middelares, 9000, Ghent, Belgium

    Laurens J. L. De Cocker

Authors
  1. Arne Vermeulen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Felice D’Arco
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Liesbeth De Groote
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Laurens J. L. De Cocker
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Arne Vermeulen.

Ethics declarations

Conflict of interest

A. Vermeulen, F. D’Arco, L. De Groote and L.J.L. De Cocker declare that they have no competing interests.

Ethical standards

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consent was obtained from the patient discussed in this report.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Vermeulen, A., D’Arco, F., De Groote, L. et al. Signal Abnormalities in Noonan Syndrome are Probably Consistent with Focal Areas of Signal Intensity (FASI). Clin Neuroradiol (2023). https://doi.org/10.1007/s00062-023-01356-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s00062-023-01356-1

Search

Navigation