Skip to main content
Log in

4. Allgemeine Definition des Myokardinfarkts 2018

Was ist neu?

4th universal definition of myocardial infarction 2018

What is new?

  • Schwerpunkt
  • Published:
Herz Aims and scope Submit manuscript

Zusammenfassung

Die 4. Allgemeine Definition des Myokardinfarkts ist eine Weiterentwicklung der Version aus dem Jahr 2012. Sie legt besonderen Wert auf die Abgrenzung zwischen Myokardschaden und Myokardinfarkt, insbesondere bei periprozedural auftretenden Troponinerhöhungen. Im Kapitel „Biomarker“ wird auf die Problematik der Vergleichbarkeit verschiedener Troponinassays und auf die Troponinverlaufskurve beim akuten Myokardinfarkt eingegangen. Die Definition der 5 Infarkttypen erfuhr geringe Veränderungen. Im Kapitel „EKG-Interpretation“ werden Hochrisikokonstellationen beschrieben. 6 neue Kapitel wurden in die aktuelle Definition eingebracht, darunter das Tako-Tsubo-Syndrom und MINOCA („myocardial infarction with non-obstructive coronary arteries“), auf die kurz eingegangen wird.

Abstract

The 4th universal definition of myocardial infarction consensus document is a further development of the document from 2012. It highlights the discrimination between myocardial injury and infarction and in particular the periprocedural occurrence of increased troponin levels. The chapter on cardiac biomarkers deals with the problems of comparison of various troponin assays and the kinetics of troponin in acute myocardial infarction. The definition of the 5 types of myocardial infarction underwent only minor changes. In the chapter on ECG interpretation high-risk constellations are described. A total of six new chapters were added to the consensus document including the takotsubo syndrome and myocardial infarction with non-obstructive coronary arteries (MINOCA), which are briefly discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3

Literatur

  1. Thygesen K, Alpert JS, Jaffe AS et al (2018) Fourth universal definition of myocardial infarction (2018). Eur Heart J. https://doi.org/10.1093/eurheartj/ehy462

    Article  PubMed  Google Scholar 

  2. Thygesen K, Alpert JS, Jaffe AS et al (2012) Third universal definition of myocardial infarction. Eur Heart J 33(20):2551–2567

    Article  PubMed  Google Scholar 

  3. Rittoo D, Jones A, Lecky B et al (2014) Elevation of cardiac troponin T, but not cardiac troponin I, in patients with neuromuscular diseases: implications for the diagnosis of myocardial infarction. J Am Coll Cardiol 63:2411–2420

    Article  CAS  PubMed  Google Scholar 

  4. http://www.ifcc.org/executive-board-and-council/eb-task-forces/task-force-on-clinical-applications-of-cardiac-bio-markers-tf-cb/

  5. Bjurman C, Larsson M, Johanson P et al (2013) Small changes in troponin T levels are common in patients with non-ST segment elevation myocardial infarc ction and are linked to higher mortality. J Am Coll Cardiol 2:1231–1238

    Article  Google Scholar 

  6. Twerenbold R, Boeddinghaus J, Nestelberger T et al (2017) Clinical use of high-sensitivity cardiac troponin in patients with suspected myocardial infarction. J Am Coll Cardiol 70:996–1012

    Article  CAS  PubMed  Google Scholar 

  7. Devereaux PJ, Xavier D, Pogue J et al (2011) Characteristics and short-term prognosis of perioperative myocardial infarction in patients undergoing noncardiac surgery: a cohort study. Ann Intern Med 154:523–528 (POISE (PeriOperative ISchemic Evaluation) Investigators)

    Article  CAS  PubMed  Google Scholar 

  8. Devereaux PJ, Chan MT, Alonso-Coello P et al (2012) Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery. JAMA 307:2295–2304

    Article  CAS  PubMed  Google Scholar 

  9. Dedic A, Lubbers MM, Schaap J et al (2016) Coronary CT angiography for suspected ACS in the era of high-sensitivity troponins: randomized multicenter study. J Am Coll Cardiol 67:16–26

    Article  PubMed  Google Scholar 

  10. Beek AM, van Rossum AC (2010) Cardiovascular magnetic resonance imaging in patients with acute myocardial infarction. Heart 96:237–243

    Article  PubMed  Google Scholar 

  11. Templin C, Ghadri JR, Diekmann J et al (2015) Clinical features and outcomes of takotsubo (stress) cardiomyopathy. N Engl J Med 373:929–938

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to J. Schofer.

Ethics declarations

Interessenkonflikt

C. Brinkmann und J. Schofer geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Brinkmann, C., Schofer, J. 4. Allgemeine Definition des Myokardinfarkts 2018. Herz 43, 681–688 (2018). https://doi.org/10.1007/s00059-018-4763-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00059-018-4763-6

Schlüsselwörter

Keywords

Navigation