Abstract
Background
The aim of this study was to evaluate the relationship between the SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery) score and left ventricular end-diastolic pressure (LVEDP) measured with an invasive method and with speckle-tracking echocardiography (STE).
Methods
The study included 124 patients who underwent cardiac catheterization. LVEDP values and coronary images were obtained for all patients. SYNTAX scores were calculated and separated into three tertiles (SYNTAX = 0, SYNTAX < 22, and SYNTAX > 22). Standard echocardiography and STE were performed on all the patients. Peak LA strain (LAs strain) in ventricular end-systole and LA strain during LA contraction (LAa strain) values were obtained with STE.
Results
In univariate analysis, a strong correlation was observed between the SYNTAX score and LAs strain and a moderate correlation with LAa strain. A moderate correlation was also found between both LAs strain and LAa strain and LVEDP. In multiple regression analysis, LAs strain and LVEDP were observed to be independent predictors of SYNTAX score.
Conclusion
LAs strain and LVEDP were observed to be independent predictors of SYNTAX scores. The relationship between LAs strain, LVEDP, and SYNTAX score could be useful in clinical practice.
Zusammenfassung
Hintergrund
Ziel der vorliegenden Studie war die Untersuchung des Zusammenhangs zwischen dem SYNTAX-Score (Synergy Between PCI With Taxus and Cardiac Surgery) und dem linksventrikulären enddiastolischen Druck (LVEDP), der mit einem invasiven Verfahren und mit der Speckle-Tracking-Echokardiographie (STE) gemessen wurde.
Methoden
In die Studie wurden 124 Patienten eingeschlossen, bei denen eine Herzkatheteruntersuchung durchgeführt wurde. Bei allen Patienten wurden die LVEDP-Werte gemessen und Aufnahmen der Koronarien gemacht. Die SYNTAX-Scores wurden berechnet und in 3 Terzile eingeteilt (SYNTAX = 0, SYNTAX < 22 und SYNTAX > 22). Sämtliche Patienten wurden mittels Standardechokardiographie und STE untersucht. Die Spitzenwerte für die linksatriale Deformation während der ventrikulären endsystolischen Kontraktion (LAs-Strain) und während der linksatrialen Kontraktion (LAa-Strain) wurden mit der STE ermittelt.
Ergebnisse
In der univariaten Analyse stellten sich eine starke Korrelation zwischen dem SYNTAX-Score und dem LAs-Strain-Wert sowie eine mäßig ausgeprägte Korrelation mit dem LAa-Strain-Wert heraus. Eine mittelgradige Korrelation wurde auch zwischen LAs-Strain und LAa-Strain sowie LVEDP beobachtet. In der multiplen Regressionsanalyse war festzustellen, dass LAs-Strain und LVEDP unabhängige Prädiktoren für den SYNTAX-Score darstellen.
Schlussfolgerung
Der LAs-Strain-Wert und der LVEDP stellten sich als unabhängige Prädiktoren für den SYNTAX-Score heraus. Der Zusammenhang zwischen LAs-Strain-Wert, LVEDP und SYNTAX-Score könnte in der klinischen Versorgung nützlich sein.
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A. Bayramoğlu, O. Bektaş, and M. Yaman state that they have no competing interest.
This article does not contain any studies with human participants or animals performed by any of the authors.
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Bayramoğlu, A., Bektaş, O. & Yaman, M. Detection of left atrial dysfunction with speckle tracking echocardiography . Herz 42, 418–424 (2017). https://doi.org/10.1007/s00059-016-4485-6
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DOI: https://doi.org/10.1007/s00059-016-4485-6