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Percutaneous edge-to-edge mitral valve repair

Current clinical evidence with the MitraClip System

Perkutane Edge-to-Edge-Mitralklappenkorrektur

Aktuelle klinische Erfahrung mit dem MitraClip-System

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Abstract

In the past few years, a myriad of technologies have been developed for percutaneous repair of the mitral valve for patients with severe mitral regurgitation (MR) and at high risk for traditional open-heart mitral valve surgery. Among them, MitraClip has emerged as the only clinically safe and effective method for percutaneous mitral valve repair. This device mimics the surgical edge-to-edge mitral valve repair initially described by Dr. Alfieri. In this article, we review the current clinical evidence on the use of the MitraClip—from the randomized control trial EVEREST II to the information derived from expert high-volume centers.

Zusammenfassung

In den letzten Jahren wurden zahlreiche Techniken für die perkutane Rekonstruktion der Mitralklappe bei Patienten mit schwerer Mitralklappeninsuffizienz und hohem Risiko für eine herkömmliche Mitralklappenoperation am offenen Herzen entwickelt. Der MitraClip hat sich daraus als die einzige klinisch sichere und wirksame Methode für die perkutane Mitralklappenrekonstruktion herausgestellt. Mit diesem Verfahren wird die erstmals von Alfieri beschriebene Edge-to-Edge-Mitralklappenoperation imitiert. Im vorliegenden Beitrag wird die aktuelle klinische Erfahrung mit dem MitraClip dargestellt – von der randomisierten kontrollierten Studie EVEREST II bis zu Informationen von erfahrenen Zentren mit hohem Durchsatz.

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Conflict of interest

On behalf of all authors, the corresponding author states that there are no conflicts of interest.

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Authors and Affiliations

  1. Department of Cardiology, Rigshospitalet Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark

    R. Estevez-Loureiro & O. Franzen MD

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  1. R. Estevez-Loureiro
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  2. O. Franzen MD
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Correspondence to O. Franzen MD.

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Estevez-Loureiro, R., Franzen, O. Percutaneous edge-to-edge mitral valve repair. Herz 38, 448–452 (2013). https://doi.org/10.1007/s00059-013-3868-1

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