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Tirofiban in Takotsubo cardiomyopathy

Atypical broken heart syndrome with extremely fast recovery: a case report

Tirofiban bei Tako-Tsubo-Kardiomyopathie

Atypisches Broken-heart-Syndrom mit extrem schneller Besserung: eine Kasuistik

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Abstract

Takotsubo cardiomyopathy, also known as broken heart syndrome, is similar to acute coronary syndrome. The absence of significant stenosis on coronary angiography and spontaneous improvement of ventricular akinesia are very important features that distinguish this syndrome from acute coronary syndromes. Despite the fact that ST segment elevations are typically encountered, atypical presentation without ECG changes should be kept in mind. We herein report the case of a 61-year-old woman who presented with mid-apical left ventricular akinesia resolving within 24 h.

Zusammenfassung

Die Tako-Tsubo-Kardiomyopathie, auch bezeichnet als Broken-heart-Syndrom, ähnelt dem akuten Koronarsyndrom. Wichtige Differenzierungsmerkmale sind die Abwesenheit relevanter koronarangiographisch nachweisbarer arterieller Stenosen und die spontane Besserung der ventrikulären Akinesie bei der Tako-Tsubo-Kardiomyopathie. Auch wenn ST-Streckenhebungen charakteristisch sind, sollte an einen atypischen klinischen Verlauf ohne EKG-Veränderungen gedacht werden. Vorgestellt wird eine 61-jährige Patientin, bei der sich die initiale linksventrikuläre Akinesie im Bereich des Apex innerhalb von 24 Stunden vollständig zurückbildete.

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Conflict of interest

On behalf of all authors, the corresponding author states that there are no conflicts of interest.

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Authors and Affiliations

  1. Faculty of Medicine, Departmant of Cardiology, Bulent Ecevit University, 67600, Kozlu/Zonguldak, Turkey

    I. Akpinar M.D., M.R. Sayin, T. Karabag, S.M. Dogan & M. Aydin

  2. Faculty of Medicine, Department of Nuclear Medicine, Bulent Ecevit University, Zonguldak, Turkey

    Y.S. Salihoglu & T. Elri

Authors
  1. I. Akpinar M.D.
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  2. Y.S. Salihoglu
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  3. M.R. Sayin
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  4. T. Elri
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  5. T. Karabag
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  6. S.M. Dogan
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  7. M. Aydin
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Corresponding author

Correspondence to I. Akpinar M.D..

Electronic supplementary material

Video 1 - In the apical four-chamber view, initial transthoracic echocardiogram revealed left ventricular akinesia in the mid-apical segments and hyperkinesia in the basal segments. (QuickTime.mov 0.7MB )

Video 2 - Control transthoracic echocardiogram in the apical four-chamber view after 1 day. Akinetic left ventricular walls returned to normokinesia. (QuickTime.mov 0.5MB )

Video 3 - Initial transthoracic echocardiogram in the apical four-chamber view by color Doppler echocardiogram; moderate mitral regurgitation was detected. (QuickTime.mov 0.3MB )

Video 4 - The mitral regurgitation disappeared 1 day later. (QuickTime.mov 0.5MB )

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Akpinar, I., Salihoglu, Y., Sayin, M. et al. Tirofiban in Takotsubo cardiomyopathy. Herz 38, 89–92 (2013). https://doi.org/10.1007/s00059-012-3664-3

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  • DOI: https://doi.org/10.1007/s00059-012-3664-3

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