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Evaluation of antioxidant activity of new constituents from the fruits of Lycium chinense

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Abstract

Two new compounds as labd-7,11-dien-3β, 13α-diol-3α-l-arabinopyranosyl-(2a → 1b)-α-l-arabinopyranosyl-(2b → 1c)-α-l-arabinopyranosyl-(2c → 1d)-α-l-arabinopyranosyl-(2d → 1e)-α-l-arabinopyranosyl-(2e → 1f)-α-l-arabinopyranosyl-(2f → 1g)-α-l-arabinopyranoside (1), and 5 (6), 11 (12), 15 (15′), 5′ (6′), 11′ (12′)-decadehydro-β-carotenyl-4β,4′β-diol-4-α-l-arabinopyranosyl-(2a → 1b)-α-l-arabinopyranosyl-(2b → 1c)-α-l-arabinopyranosyl-(2c → 1d)-β-l-arabinopyranosido-4′-α-l-arabinopyranosyl-(2e → 1f)-α-l-arabinopyranosyl-(2f → 1g)-α-l-arabinopyranosyl-(2g → 1h)-α-l-arabinopyranosyl-(2h → 1i)-β-l-arabinopyranoside (2) along with known compound have been isolated from the methanol extract of fruits of Lycium chinense. Their chemical structures were established with the help of physical, chemical, and spectroscopic methods. The compounds 1 and 2 were investigated for scavenging of the diphenylpicrylhydrazyl (DPPH) radical scavenging activity, reducing power, and the phosphomolybdenum activity, and the results demonstrate that the compound (1) has potential as a natural antioxidant whereas the compound (2) exhibited moderate antioxidant activity.

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Acknowledgments

This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education, Science, and Technology (2011-0015691).

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Authors and Affiliations

  1. Department of Applied Bioscience, Konkuk University, Seoul, 143-701, South Korea

    Ill-Min Chung, Praveen Nagella & Ateeque Ahmad

  2. Department of Pharamcognosy and Phytochemistry, Hamdard University, New Delhi, 110062, India

    Mohd Ali

  3. Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia

    Nasir Ali Siddiqui

  4. Central Institute of Medicinal and Aromatic Plants, Lucknow, India

    Ateeque Ahmad

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  1. Ill-Min Chung
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  2. Mohd Ali
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  3. Praveen Nagella
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  4. Nasir Ali Siddiqui
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  5. Ateeque Ahmad
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Correspondence to Ateeque Ahmad.

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Chung, IM., Ali, M., Nagella, P. et al. Evaluation of antioxidant activity of new constituents from the fruits of Lycium chinense . Med Chem Res 23, 3852–3860 (2014). https://doi.org/10.1007/s00044-014-0968-2

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