Abstract
Tea (Camellia sinensis, Theaceae) is the second most consumed beverages in the world, next to water in terms of worldwide popularity. The chemical components of green tea chiefly include polyphenols, caffeine, and amino acids. Green tea is rich in catechins, of which (−)-epigallocatechin-3-gallate is the most abundant. As described in literature, green tea and its polyphenols are beneficial in curing a wide variety of diseases like cancer, diabetes, cardiovascular disease, obesity, etc. It also has antimicrobial activity, protects from solar radiations, and possesses neuroprotective properties. The current review article focuses on pharmacological profile associated with Green tea and its polyphenols. We hope that this review will expose areas for further study and encourage research on important public health issue.
This is a preview of subscription content, access via your institution.


References
Abdel-Raheem IT, El-Sherbiny GA, Taye A (2010) Green tea ameliorates renal oxidative damage induced by gentamicin in rats. Pak J Pharm Sci 23:21–28
Akgun H, Berk B, Erol DD, Mercanoglu G, Bayrak OF, Caglayan B, Dedeagac A, Kurnaz IA (2009) Nitric oxide releasing derivatives of [(2-chloroethyl)ureido] benzoic acid esters as potential antineoplastic agents. Turk J Chem 33:107–121
Aktas O, Prozorovski T, Smorodchenko A, Savaskan NE, Lauster R, Kloetzel P-M, Infante-Duarte C, Brocke S, Zipp F (2004) Green tea epigallocatechin-3-gallate mediates T cellular NF-κB inhibition and exerts neuroprotection in autoimmune encephalomyelitis. J Immunol 173:5794–5800
Al-Attar AM, Zari TA (2010) Influences of crude extract of tea leaves, Camellia sinensis, on streptozotocin diabetic male albino mice. Saudi J Biol Sci 17:295–301
Atoui AK, Mansouri A, Boskou G, Kefalas P (2004) Tea and herbal infusions: their antioxidant activity and phenolic profile. Food Chem 89:27–36
Bisht GS, Rawat DS, Kumar A, Kumar R, Pashaa S (2007) Antimicrobial activity of rationally designed amino terminal modified peptides. Bioorg Med Chem Lett 17:4343–4346
Blanco AR, Sudano-Roccaro A, Spoto GC, Nostro A, Rusciano D (2005) Epigallocatechin gallate inhibits biofilm formation by ocular staphylococcal isolates. Antimicrob Agents Chemother 49:4339–4343
Boschmann M, Thielecke F (2007) The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: a pilot study. J Am Coll Nutr 26:389S–395S
Bose M, Lambert JD, Ju J, Reuhl KR, Shapses SA, Yang CS (2008) The major green tea polyphenol, (−)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat–fed mice. J Nutr 138:1677–1683
Cabrera C, Artacho R, Giménez R (2006) Beneficial effects of green tea—a review. J Am Coll Nutr 25:79–99
Carlson JR, Bauer BA, Vincent A, Limburg PJ, Wilson T (2007) Reading the tea leaves: anticarcinogenic properties of (−)-epigallocatechin-3-gallate. Mayo Clin Proc 82:725–732
Carvalh M, Jeronimo C, Valentao P, Andrad PB, Silva BM (2010) Green tea: a promising anticancer agent for renal cell carcinoma. Food Chem 122:49–54
Chacko SM, Thambi PT, Kuttan R, Nishigaki I (2010) Beneficial effects of green tea: a literature review. Chin Med 5:13
Chan C-M, Huang J-H, Lin H-H, Chiang H-S, Chen B-H, Hong J-Y, Hung C-F (2008) Protective effects of (−)-epigallocatechin gallate on UVA-induced damage in ARPE19 cells. Mol Vis 14:2528–2534
Chan C-M, Huang J-H, Chiang H-S, Wu W-B, Lin H-H, Hong J-Y, Hung C-F (2010) Effects of (−)-epigallocatechin gallate on RPE cell migration and adhesion. Mol Vis 16:586–595
Chen A, Zhang L, Xu J, Tang J (2002) The antioxidant (−)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression. Biochem J 368:695–704
Chen X, Lin Z, Ye Y, Zhang R, Yin J, Jiang Y, Wan H (2010) Suppression of diabetes in non-obese diabetic (NOD) mice by oral administration of water-soluble and alkali-soluble polysaccharide conjugates prepared from green tea. Carbohydr Polym 82:28–33
Cheng TO (2006) All teas are not created equal the Chinese green tea and cardiovascular health. Int J Cardiol 108:301–308
Chrostek L, Tomaszewski W, Szmitkowski M (2005) The effect of green tea on the activity of aldehyde dehydrogenase (ALDH) in the liver of rats during chronic ethanol consumption. Rocz Akad Med Bialymst 50:220–223
Chyu K-Y, Babbidge SM, Zhao X, Dandillaya R, Rietveld AG, Yano J, Dimayuga P, Cercek B, Shah PK (2004) Differential effects of green tea-derived catechin on developing versus established atherosclerosis in apolipoprotein E-Null mice. Circulation 109:2448–2453
Clement Y (2009) Can green tea do that? A literature review of the clinical evidence. Prev Med 49:83–87
Daisuke U, Satomi Y, Koji Y, Hirofumi T (2008) Green tea polyphenol epigallocatechin-3-gallate signaling pathway through 67-kDa Laminin receptor. J Biol Chem 283:3050–3058
Dulloo AG, Seydoux J, Girardier L, Chantre P, Vandermander J (2000) Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity. Int J Obes 24:252–258
Ehrnhoefer DE, Duennwald M, Markovic P, Wacker JL, Engemann S, Roark M, Legleiter J, Marsh JL, Thompson LM, Lindquist S, Muchowski PJ, Wanker EE (2006) Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington’s disease models. Hum Mol Genet 15:2743–2751
El-Shahat AE, Gabr A, Meki A-R, Mehana E-S (2009) Altered testicular morphology and oxidative stress induced by cadmium in experimental rats and protective effect of simultaneous green tea extract. Int J Morphol 27:757–764
Finkel R, Clark AM, Cubeddu XL (2009) Antihypertensives. In: Harvey RA, Champe PC (eds) Lippincott’s illustrated reviews: pharmacology, 4th edn. Lippincott Williams & Wilkins, Maryland, p 215
Frei B, Higdon JV (2003) Antioxidant activity of tea polyphenols in vivo: evidence from animal studies. J Nutr 133:3275S–3284S
Gordon NC, Wareham DW (2010) Antimicrobial activity of the green tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia. Int J Antimicrob Agent 36:129–131
Hao J, Kim C-H, Ha T-S, Ahn H-Y (2007) Epigallocatechin-3 gallate prevents cardiac hypertrophy induced by pressure overload in rats. J Vet Sci 8:121–129
Hara-Kudo Y, Yamasaki A, Sasaki M, Okubo T, Minai Y, Haga M, Kondo K, Sugita-Konishi Y (2005) Antibacterial action on pathogenic bacterial spore by green tea catechins. J Sci Food Agric 85:2354–2361
Hauber I, Hohenberg H, Holstermann B, Hunstein W, Hauber J (2009) The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection. PNAS 106:9033–9038
Hirasawa M, Takada K (2004) Multiple effects of green tea catechin on the antifungal activity of antimycotics against Candida albicans. J Antimicrob Chemother 53:225–229
Hirasawa M, Takada K, Makimura M, Otake S (2002) Improvement of periodontal status by green tea catechin using a local delivery system: a clinical pilot study. J Periodont Res 37:433–438
Hofmann CS, Sonenshein GE (2003) Green tea polyphenol epigallocatechin-3 gallate induces apoptosis of proliferating vascular smooth muscle cells via activation of p53. FASEB J 17:702–704
Hossain P, Kawar B, El Nahas M (2007) Obesity and diabetes in the developing world—a growing challenge. N Engl J Med 356:213–215
Imanishi N, Tuji Y, Katada Y, Maruhashi M, Konosu S, Mantani N, Terasawa K, Ochiai H (2002) Additional inhibitory effect of tea extra on the growth of Influenza A and B viruses in MDCK cells. Microbiol Immunol 46:491–494
Joshi S, Bisht GS, Rawat DS, Kumar A, Kumar R, Maiti S, Pasha S (2010) Interaction studies of novel cell selective antimicrobial peptides with model membranes and E. coli ATCC 11775. Biochim Biophys Acta 1798:1864–1875
Juneja VK, Bari ML, Inatsu Y, Kawamoto S, Friedman M (2007) Control of Clostridium perfringens spores by green tea leaf extracts during cooling of cooked ground beef, chicken, and pork. J Food Prot 70:1429–1433
Kang KW, Oh SJ, Ryu SY, Song GY, Kim B, Kang JS, Kim SK (2010) Evaluation of the total oxy-radical scavenging capacity of catechins isolated from green tea. Food Chem 121:1089–1094
Karaca T, Yoruk M, Yoruk IH, Uslu S (2010) Effects of extracts of green tea and ginseng on pancreatic beta cells and levels of serum glucose, insulin, cholesterol and triglycerides in rats with experimentally streptozotocin-induced diabetes: a histochemical and immunohistochemical study. J Anim Vet Adv 9:102–107
Kaszkin M, Beck K, Eberhardt W, Pfeilschifter J (2004) Unravelling green tea’s mechanisms of action: more than meets the eye. Mol Pharmacol 65:15–17
Katiyar SK, Mukhtar H (2001) Green tea polyphenol (−)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. J Leukoc Biol 69:719–726
Katiyar SK, Afaq F, Perez A, Mukhtar H (2001) Green tea polyphenol (−)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress. Carcinogenesis 22:287–294
Kim YW, Bae SM, Lee JM, Namkoong SE, Han SJ, Lee BR, Lee IP, Kim SH, Lee YJ, Kim CK, Kim Y-W, Ahn WS (2004) Activity of green tea polyphenol epigallocatechin-3-gallate against ovarian carcinoma cell lines. Cancer Res Treat 36:315–323
Kim SH, Lee LS, Bae SM, Han SJ, Lee BR, Ahn WS (2008) Antimicrobial and antifungal effects of a green tea extract against vaginal pathogens. J Womens Med 1:27–36
Koizumi Y, Tsubono Y, Nakaya N, Nishino Y, Shibuya D, Matsuoka H, Tsuji I (2003) No association between green tea and the risk of gastric cancer: pooled analysis of two prospective studies in Japan. Cancer Epidemiol Biomark Prev 12:472–473
Kuriyama S, Hozawa A, Ohmori K, Shimazu T, Matsui T, Ebihara S, Awata S, Nagatomi R, Arai H, Tsuji I (2006) Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project. Am J Clin Nutr 83:355–361
Lee M-J, Lambert JD, Prabhu S, Meng X, Lu H, Maliakal P, Ho C-T, Yang CS (2004) Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract. Cancer Epidemiol Biomark Prev 13:132–137
Leung LK, Su Y, Chen R, Zhang Z, Huang Y, Chen Z-Y (2001) Theaflavins in black tea and catechins in green tea are equally effective antioxidants. J Nutr 131:2248–2251
Levites Y, Amit T, Mandel S, Youdim MBH (2003) Neuroprotection and neurorescue against Aβ toxicity and PKC-dependent release of non-amyloidogenic soluble precursor protein by green tea polyphenol (−)-epigallocatechin-3-gallate. FASEB J 17:952–954
Lorenz M, Wessler S, Follmann E, Michaelis W, Dusterhoft T, Baumann G, Stangl K, Stangl V (2004) A constituent of green tea, epigallocatechin-3-gallate, activates endothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and Akt-dependent pathway and leads to endothelial-dependent vasorelaxation. J Biol Chem 279:6190–6195
Maeta K, Nomura W, Takatsume Y, Izawa S, Inoue Y (2007) Green tea polyphenols function as prooxidants to activate oxidative-stress-responsive transcription factors in yeasts. Appl Environ Microbiol 73:572–580
Maki KC, Reeves MS, Farmer M, Yasunaga K, Matsuo N, Katsuragi Y, Komikado M, Tokimitsu I, Wilder D, Jones F, Blumberg JB, Cartwright Y (2009) Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults. J Nutr 139:264–270
Maruyama K, Iso H, Sasaki S, Fukino Y (2009) The association between concentrations of green tea and blood glucose levels. J Clin Biochem Nutr 44:41–45
Matsubara S, Shibata H, Ishikawa F, Yokokura T, Takahashi M, Sugimura T, Wakabayashi K (2003) Suppression of Helicobacter pylori-induced gastritis by green tea extract in Mongolian gerbils. Biochem Biophys Res Commun 310:715–719
McNaught JG (1906) On the action of cold or lukewarm tea on Bacillus typhosus. J Royal Army Medical Corps 7:372–373
Meeran SM, Akhtar S, Katiyar SK (2009) Inhibition of UVB-induced skin tumor development by drinking green tea polyphenols is mediated through DNA repair and subsequent inhibition of inflammation. J Invest Dermatol 129:1258–1270
Mildner-Szkudlarz S, Zawirska-Wojtasiak R, Obuchowski W, GÏŒslÃnski M (2009) Evaluation of antioxidant activity of green tea extract and its effect on the biscuits lipid fraction oxidative stability. J Food Sci 74:S362–S370
Mimoto J, Kiura K, Matsuo K, Yoshino T, Takata I, Ueoka H, Kataoka M, Harada M (2000) (−)-Epigallocatechin gallate can prevent cisplatin-induced lung tumorigenesis im A/J mice. Carcinogenesis 21:915–919
Miura T, Koike T, Ishida T (2005) Antidiabetic activity of green tea (Thea sinensis L.) in genetically Type 2 diabetic mice. J Health Sci 51:708–710
Mughal T, Tahir A, Qureshi S, Nazir T, Rasheed M (2010) Antibacterial activity of black tea against streptococcus mutans and its synergism with antibiotics. J Appl Pharm 2:60–67
Mukhtar H, Ahmad N (2000) Tea polyphenols: prevention of cancer and optimizing health. Am J Clin Nutr 71:1698S–1702S
Nagao T, Hase T, Tokimitsu I (2007) A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity 15:1473–1483
Navarro-MartÃnez MD, Navarro-Perán E, Cabezas-Herrera J, Ruiz-GÏŒmez J, GarcÃa-Cánovas F, RodrÃguez-LÏŒpez JN (2005) Antifolate activity of epigallocatechin gallate against Stenotrophomonas maltophilia. Antimicrob Agents Chemother 49:2914–2920
Negishi H, Xu J-W, Ikeda K, Njelekela M, Nara Y, Yamori Y (2004) Black and green tea polyphenols attenuate blood pressure increases in stroke-prone spontaneously hypertensive rats. J Nutr 134:38–42
Ng T-P, Feng L, Niti M, Kua E-H, Yap K-B (2008) Tea consumption and cognitive impairment and decline in older Chinese adults. Am J Clin Nutr 88:224–231
Papparella I, Ceolotto G, Montemurro D, Antonello M, Garbisa S, Rossi GP, Semplicini A (2008) Green tea attenuates Angiotensin II-induced cardiac hypertrophy in rats by modulating reactive oxygen species production and the Src/epidermal growth factor receptor/Akt signaling pathway. J Nutr 138:1596–1601
Park JH, Jin JY, Baek WK, Park SH, Sung HY, Kim YK, Lee J, Song DK (2009) Ambivalent role of gallated catechins in glucose tolerance in humans: a novel insight into non-absorbable gallated catechin-derived inhibitors of glucose absorption. J Physiol Pharmacol 60:101–109
Potenza MA, Marasciulo FL, Tarquinio M, Tiravanti E, Colantuono G, Federici A, Kim J, Quon MJ, Montagnani M (2007) EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardialnI/R injury in SHR. Am J Physiol Endocrinol Metab 292:E1378–E1387
Rains TM, Agarwal S, Makia KC (2011) Antiobesity effects of green tea catechins: a mechanistic review. J Nutri Biochem 22:1–7
Rezai-Zadeh K, Shytle D, Sun N, Mori T, Hou H, Jeanniton D, Ehrhart J, Townsend K, Zeng J, Morgan D, Hardy J, Town T, Tan J (2005) Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in alzheimer transgenic mice. J Neurosci 25:8807–8814
Rietveld A, Wiseman S (2003) Antioxidant effects of tea: evidence from human clinical trials. J Nutr 133:3285S–3292S
Roy AM, Baliga MS, Katiyar SK (2005) Epigallocatechin-3-gallate induces apoptosis in estrogen receptor—negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation. Mol Cancer Ther 4:81–90
Rudelle S, Ferruzzi MG, Cristiani I, Moulin J, Macé K, Acheson KJ, Tappy L (2007) Effect of a thermogenic beverage on 24-hour energy metabolism in humans. Obesity 15:349–355
Ruggiero P, Rossi G, Tombola F, Pancotto L, Lauretti L, Giudice GD, Zoratti M (2007) Red wine and green tea reduce H pylori—or VacA-induced gastritis in a mouse model. World J Gastroenterol 13:349–354
Sakanaka S, Juneja LR, Taniguchi M (2000) Antimicrobial effects of green tea polyphenols on thermophilic spore-forming bacteria. J Biosci Bioeng 90:81–85
Sartippour MR, Pietras R, Marquez-Garban DC, Chen H-W, Heber D, Henning SM, Sartippour G, Zhang L, Lu M, Weinberg O, Rao JY, Brooks MN (2006) The combination of green tea and tamoxifen is effective against breast cancer. Carcinogenesis 27:2424–2433
Sharangi AB (2009) Medicinal and therapeutic potentialities of tea (Camellia sinensis L.)—a review. Food Res Int 42:529–535
Sinha D, Roy S, Roy M (2010) Antioxidant potential of tea reduces arsenite induced oxidative stress in Swiss albino mice. Food Chem Toxicol 48:1032–1039
Song J-M, Lee K-H, Seong B-L (2005) Antiviral effect of catechins in green tea on influenza virus. Antivir Res 68:66–74
Stapleton PD, Gettert J, Taylor PW (2006) Epicatechin gallate, a component of green tea, reduces halotolerance in Staphylococcus aureus. Int J Food Microbiol 111:276–279
Stoicov C, Saffari R, Houghton J (2009) Green tea inhibits Helicobacter growth in vivo and in vitro. Int J Antimicrob Agent 33:473–478
Suganuma M, Okabe S, Kai Y, Sueoka N, Sueoka E, Fujiki H (1999) Synergistic effects of (−)-epigallocatechin gallate with (−)-epicatechin, Sulindac, or Tamoxifen on cancer-preventive activity in the human lung cancer cell line PC-9. Cancer Res 59:44–47
Sutherland BA, Shaw OM, Clarkson AN, Jackson DM, Sammut IA, Appleton I (2005) Neuroprotective effects of (−)-epigallocatechin gallate after hypoxia-ischemia-induced brain damage: novel mechanisms of action. FASEB J 19:258–260
Tanaka T, Ishii T, Mizuno D, Mori T, Yamaji R, Nakamura Y, Kumazawa S, Nakayama T, Akagawa M (2011) (−)-Epigallocatechin-3-gallate suppresses growth of AZ521 human gastric cancer cells by targeting the DEAD-box RNA helicase p68. Free Radic Biol Med 50:1324–1335
Taylor PW, Hamilton-Miller JMT, Stapleton PD (2005) Antimicrobial properties of green tea catechins. Food Sci Technol Bull 2:71–81
Tsubono Y, Nishino Y, Komatsu S, Chung-Cheng H, Kanemura S, Tsuji I, Nakatsuka H, Fukao A, Satoh H, Hisamichi S (2001) Green tea and the risk of gastric cancer in Japan. N Engl J Med 344:632–636
USDA Database for the Flavonoid Content of Selected Foods. Nutrient Data Laboratory. Food Composition Laboratory. Beltsville Human Nutrition Research Center. Nutrient Data Laboratory. United States Department of Agriculture. Available at: http://www.ars.usda.gov/SP2UserFiles/Place/12354500/Data/Flav/Flav02-1.pdf. Accessed February 20, 2011
Waltner-Law ME, Wang XL, Law BK, Hall RK, Nawano M, Granner DK (2002) Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production. J Biol Chem 277:34933–34940
West PWJ, Mathew TC, Miller NJ, Electricwala Q (2001) The effect of green tea on the growth and morphology of methicillin-resistant and methicillin-susceptible Staphylococcus aureus. J Nutr Environ Med 11:263–269
Williamson MP, McCormick TG, Nance CL, Shearer WT (2006) Epigallocatechin gallate, the main polyphenol in green tea, binds to the T-cell receptor, CD4: Potential for HIV-1 therapy. J Allergy Clin Immunol 118:1369–1374
Wolfram S, Raederstorff D, Preller M, Wang Y, Teixeira SR, Riegger C, Weber P (2006) Epigallocatechin gallate supplementation alleviates diabetes in rodents. J Nutr 136:2512–2518
Xu JZ, Yeung SYV, Chang Q, Huang Y, Chen ZY (2004) Comparison of antioxidant activity and bioavailability of tea epicatechins with their epimers. Br J Nutr 91:873–881
Yang G, Shu X-O, Li H, Chow W-H, Ji B-T, Zhang X, Gao Y-T, Zheng W (2007) Prospective cohort study of green tea consumption and colorectal cancer risk in women. Cancer Epidemiol Biomark Prev 16:1219–1223
Yao K, Ye P-P, Zhang L, Tan J, Tang X-J, Zhang Y-D (2008) Epigallocatechin gallate protects against oxidative stress-induced mitochondria-dependent apoptosis in human lens epithelial cells. Mol Vis 14:217–223
Yee Y-K, Koo MW-L (2000) Anti-Helicobacter pylori activity of Chinese tea: in vitro study. Aliment Pharmacol Ther 14:635–638
Yi S-M, Zhu J-L, Fu L–L, Li J-R (2010) Tea polyphenols inhibit Pseudomonas aeruginosa through damage to the cell membrane. Int J Food Microbiol 144:111–117
Young IS, Woodside JV (2001) Antioxidants in health and disease. J Clin Pathol 54:176–186
Yuan J-M, Koh W-P, Sun C-L, Lee H-P, Yu MC (2005) Green tea intake, ACE gene polymorphism and breast cancer risk among Chinese women in Singapore. Carcinogenesis 26:1389–1394
Yung SL, Yao JT, Jyh ST, Jen KL (2003) Factors affecting the levels of tea polyphenols and caffeine in tea leaves. J Agric Food Chem 5:1864–1873
Zapora E, Hołub M, Waszkiewicz E, Dąbrowska M, Skrzydlewska E (2009) Green tea effect on antioxidant status of erythrocytes and on haematological parameters in rats. Bull Vet Inst Pulawy 53:139–145
Zaveri NT (2006) Green tea and its polyphenolic catechins: Medicinal uses in cancer and noncancer applications. Life Sci 78:2073–2080
Zhang Y-M, Rock CO (2004) Evaluation of epigallocatechin gallate and related plant polyphenols as inhibitors of the FabG and FabI reductases of bacterial Type II fatty-acid synthase. J Biol Chem 279:30994–31001
Zhang ZF, Li Q, Liang J, Dai XQ, Ding Y, Wang JB, Li Y (2010) Epigallocatechin-3-O-gallate (EGCG) protects the insulin sensitivity in rat L6 muscle cells exposed to dexamethasone condition. Phytomedicine 17:14–18
Zheng G, Sayama K, Ohkubo T, Juneja LR, Oguni I (2004) Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice. In Vivo 18:3–10
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bansal, S., Syan, N., Mathur, P. et al. Pharmacological profile of green tea and its polyphenols: a review. Med Chem Res 21, 3347–3360 (2012). https://doi.org/10.1007/s00044-011-9800-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00044-011-9800-4