Protein–polysaccharides of Trametes versicolor: production and biological activities

Abstract

Extracellular- (E-PPS) and intracellular-protein–polysaccharides (I-PPS) complexes were produced by Trametes versicolor in submerged cultures with different carbon sources. The highest extracellular-(EPS) and intracellular-polysaccharide (IPS) concentration in the complexes was obtained with tomato pomace culture. DPPH radical scavenging for E-PPS and I-PPS produced by liter of culture was equivallent to 2.115 ± 0.227 and 1.374 ± 0.364 g of ascorbic acid, respectively. These complexes showed a protector effect in the oxidation of erythrocyte membranes and had ability to inhibit the hemolysis and methemoglobin synthesis in stressed erythrocytes. These results suggest that extracellular- and intracellular- polysaccharides produced are important bioactive compounds with medicinal potential.

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Correspondence to A. Teresa Caldeira.

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Santos Arteiro, J.M., Rosário Martins, M., Salvador, C. et al. Protein–polysaccharides of Trametes versicolor: production and biological activities. Med Chem Res 21, 937–943 (2012). https://doi.org/10.1007/s00044-011-9604-6

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Keywords

  • Protein–polysaccharides
  • Trametes versicolor
  • Submerged fermentation
  • Edible mushrooms
  • Antioxidant properties