Chromatographic separation of Rhus tripartitum (Anacardiaceae) chemical components revealed the presence of four main natural substances: a new biflavonoid masazinoflavanone (S1), myricetin (S2), (-)-lyoniresinol 3α-O-β-D-glucopyranoside (S3), and (-)-methyl shikimate (S4). The anti-inflammatory activity of the new biflavonoid substance was performed. Compared with the standard drug dexamethasone, the biflavonoid substance masazinoflavanone (S1) inhibited in a dose-related manner carrageenan-induced paw edema in rats. Antiradical scavenging capacities of extracts and natural substances issued from Rhus tripartitum were tested using free radical forms of ABTS and DPPH. The Trolox Equivalent Antioxidant Capacity (TEAC) assay shows values of 1.92, 1.39, 1.25, 2.40, and 1.58 mM Trolox/mg sample respectively for the chloroformic extract, the ethyl acetate extract, (S1), (S2), and (S3). Values revealed form the total phenolic content assay were 299.3, 372.3, 99.1, and 235.7 mg Catechin/g extract respectively for the chloroformic, ethyl acetate, ethyl acetate/methanol, and methanolic extracts.
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Mahjoub, M.A., Ammar, S., Edziri, H. et al. Anti-inflammatory and antioxidant activities of some extracts and pure natural products isolated from Rhus tripartitum (Ucria). Med Chem Res 19, 271–282 (2010). https://doi.org/10.1007/s00044-009-9190-z
- Rhus tripartitum
- New biflavonoid
- Anti-inflammatory activity
- Antioxidant activity
- Total phenolic content