Isolation and characterization of new compounds from seeds of Nigella sativa

Abstract

Two new triterpenoids were isolated from the n-hexane extract of seeds of Nigella sativa Linn. and identified as cycloart-23-methyl-7,20,22-triene-3β,30-diol (1) and cycloart-3-one-7,22-diene-24-ol (2). In addition, two aliphatic compounds and two known sugars were isolated from alcohol extract, and identified as 4-hydroxy undecyl nonanoate (3), 14,20-dimethyl heptacosanol (4), maltose (5), and sucrose (6). They were characterized on the basis of spectral analysis and by comparing literature data. Extraction and transportation study of sugars were also investigated, which evaluated biological phenomena.

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Acknowledgements

The authors would like to thank RSIC, CDRI, LUCKNOW and RSIC, IIT-BOMBAY, for spectral analysis.

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Correspondence to Meenal Gupta.

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Mehta, B.K., Sharma, U., Agrawal, S. et al. Isolation and characterization of new compounds from seeds of Nigella sativa . Med Chem Res 17, 462–473 (2008). https://doi.org/10.1007/s00044-007-9080-1

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Keywords

  • Triterpenoids
  • Sugars
  • Seed
  • Transportation studies
  • Nigella sativa