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STRUCTURAL CHARACTERISATION OF AN IMMUNOMODULATING POLYSACCHARIDE ISOLATED FROM AQUEOUS EXTRACT OF PLEUROTUS FLORIDA FRUIT-BODIES

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Abstract

The water-soluble glucan was obtained from Pleurotus florida fruit bodies by hot water extraction, ethanol precipitation, DEAE cellulose dialysis and Sephadex G-75 gel filtration. The structural information of the glucan was achieved by chemical (hydrolysis, methylation, periodate oxidation) and spectroscopic (1H and 13C) analyses, indicated a repeating unit built up of (1→6)-linked D-glucose. The following structure has been determined for the repeating unit: →6)-α-D-Glcp-(1→ This fraction exhibited significant macrophage activity through the release of nitric oxide

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Authors and Affiliations

  1. Department of Chemistry & Chemical Technology, Vidyasagar University, Midnapore, West Bengal, 721 102, India

    Dilip Rout, Soumitra Mondal, Indranil Chakraborty, Malay Pramanik & Syed Sirajul Islam

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  1. Dilip Rout
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  2. Soumitra Mondal
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  3. Indranil Chakraborty
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  4. Malay Pramanik
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  5. Syed Sirajul Islam
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Correspondence to Syed Sirajul Islam.

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Rout, D., Mondal, S., Chakraborty, I. et al. STRUCTURAL CHARACTERISATION OF AN IMMUNOMODULATING POLYSACCHARIDE ISOLATED FROM AQUEOUS EXTRACT OF PLEUROTUS FLORIDA FRUIT-BODIES. Med Chem Res 13, 509–517 (2004). https://doi.org/10.1007/s00044-004-0050-6

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  • DOI: https://doi.org/10.1007/s00044-004-0050-6

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