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Numerical simulations of a reduced model for blood coagulation

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Abstract

In this work, the three-dimensional numerical resolution of a complex mathematical model for the blood coagulation process is presented. The model was illustrated in Fasano et al. (Clin Hemorheol Microcirc 51:1–14, 2012), Pavlova et al. (Theor Biol 380:367–379, 2015). It incorporates the action of the biochemical and cellular components of blood as well as the effects of the flow. The model is characterized by a reduction in the biochemical network and considers the impact of the blood slip at the vessel wall. Numerical results showing the capacity of the model to predict different perturbations in the hemostatic system are discussed.

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Authors and Affiliations

  1. CEMAT, IST, Universidade de Lisboa, Lisbon, Portugal

    Jevgenija Pavlova & Adélia Sequeira

  2. Dipartimento di Matematica, “U. Dini”, Università degli studi di Firenze, Florence, Italy

    Antonio Fasano (Scientific Manager)

  3. FIAB SpA, Florence, Italy

    Antonio Fasano (Scientific Manager)

  4. Istituto di Analisi dei Sistemi ed Informatica (IASI) Antonio Ruberti, CNR, Rome, Italy

    Antonio Fasano (Scientific Manager)

  5. Departamento de Matemática, IST, Universidade de Lisboa, Lisbon, Portugal

    Adélia Sequeira

Authors
  1. Jevgenija Pavlova
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  2. Antonio Fasano
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  3. Adélia Sequeira
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Correspondence to Adélia Sequeira.

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Pavlova, J., Fasano, A. & Sequeira, A. Numerical simulations of a reduced model for blood coagulation. Z. Angew. Math. Phys. 67, 28 (2016). https://doi.org/10.1007/s00033-015-0610-2

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  • DOI: https://doi.org/10.1007/s00033-015-0610-2

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