Skip to main content
Log in

The limited role of most circRNAs as sponges for microRNAs

  • Commentary
  • Published:
Cellular and Molecular Life Sciences Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Availability of data and materials

Not applicable. Any additional information required to reanalyze the data reported in this paper is available from the corresponding author upon request.

References

  1. Fu H et al (2022) CircACTR2 in macrophages promotes renal fibrosis by activating macrophage inflammation and epithelial-mesenchymal transition of renal tubular epithelial cells. Cell Mol Life Sci 79:253

    Article  CAS  Google Scholar 

  2. Guo JU et al (2014) Expanded identification and characterization of mammalian circular RNAs. Genome Biol 15:409

    Article  Google Scholar 

  3. Li X et al (2018) The biogenesis, functions, and challenges of circular RNAs. Mol Cell 71:428–442

    Article  CAS  Google Scholar 

  4. Kim E et al (2021) Emerging functions of circular RNA in aging. Trends Genet 37:819–829

    Article  CAS  Google Scholar 

  5. He AT et al (2021) Targeting circular RNAs as a therapeutic approach: current strategies and challenges. Signal Transduct Target Ther 6:185

    Article  CAS  Google Scholar 

Download references

Funding

This work was funded by the National Undergraduate Training Program for Innovation and Entrepreneurship from the Ministry of Education of the People's Republic of China and Ningbo University (201811646025 to Ye-Zhao Wang), the Student Research and Innovation Program of Ningbo University (2017SRIP1918, 2018SRIP2507, and 2019SRIP1902 to Ye-Zhao Wang), the Jiang Xinghao Student Scientific Research Talent Cultivation Fund of Ningbo University to Ye-Zhao Wang, the Jiang Xinghao Student Scientific Research Achievement Award of Ningbo University to Ye-Zhao Wang, and the K. C. Wong Magna Found in Ningbo University to Ye-Zhao Wang.

Author information

Authors and Affiliations

Authors

Contributions

The author apologizes that space constraints prevent him from citing all relevant publications. Ye-Zhao Wang wrote and edited the manuscript and contributed toward the design and structure of the manuscript.Ye-Zhao Wang had the idea for the study, received the grant supports and had full access to all data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis, designed the study, study supervision, collection of data, processed statistical data, analysis and interpretation of data, study concept, concept design and writing, drafting the manuscript, critical review of the manuscript for important intellectual content. Substantial contributions to the conception or design of the work; and drafting the work; and final approval of the version to be published. Ye-Zhao Wang would just like to forward my deepest appreciation and thanks to Nankai University School of Medicine. Ye-Zhao Wang would like to thank also Professor Rong-Cun Yang. Without whom this work would not have been possible. Ye-Zhao Wang would like to express his heartfelt thanks to everyone of Nankai University School of Medicine.

Corresponding author

Correspondence to Ye-Zhao Wang.

Ethics declarations

Conflict of interest

The author declares that there is no conflict of interest.

Ethics approval and consent to participate

Not applicable.

Consent for publication

Not applicable.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wang, YZ. The limited role of most circRNAs as sponges for microRNAs. Cell. Mol. Life Sci. 79, 299 (2022). https://doi.org/10.1007/s00018-022-04370-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s00018-022-04370-7

Navigation