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The “STK38-XPO1 axis”: its general relevance and mechanistic underpinnings remain to be further characterized

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References

  1. Martin AP, Aushev VN, Zalcman G, Camonis JH (2020) The STK38-XPO1 axis, a new actor in physiology and cancer. Cell Mol Life Sci. https://doi.org/10.1007/s00018-020-03690-w

    Article  PubMed  PubMed Central  Google Scholar 

  2. Martin AP, Jacquemyn M, Lipecka J, Chhuon C, Aushev VN, Meunier B, Singh MK, Carpi N, Piel M, Codogno P, Hergovich A, Parrini MC, Zalcman G, Guerrera IC, Daelemans D, Camonis JH (2019) STK38 kinase acts as XPO1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoes. EMBO 20(11):e48150. https://doi.org/10.15252/embr.201948150 (Epub 23 Sep 2019)

    Article  CAS  Google Scholar 

  3. The International Mouse Phenotyping Consortium. Accessed Dec 2020. https://www.mousephenotype.org/data/genes/MGI:2144013#phenotypesTab

  4. Cornils H, Stegert MR, Hergovich A, Hynx D, Schmitz D, Dirnhofer S et al (2010) Ablation of the kinase NDR1 predisposes mice to the development of T cell lymphoma. Sci Signal 3(126):47

    Article  Google Scholar 

  5. Sendino M, Omaetxebarria MJ, Rodríguez JA (2018) Hitting a moving target: inhibition of the nuclear export receptor XPO1/CRM1 as a therapeutic approach in cancer. Cancer Drug Resist 1:139–163

    Google Scholar 

  6. Azmi AS, Uddin MH, Mohammad RM (2020) The nuclear export protein XPO1—from biology to targeted therapy. Nat Rev Clin Oncol. https://doi.org/10.1038/s41571-020-00442-4

    Article  PubMed  Google Scholar 

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  1. Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country (UPV/EHU), 48940, Leioa, Spain

    Jose Antonio Rodriguez

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  1. Jose Antonio Rodriguez
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Correspondence to Jose Antonio Rodriguez.

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Rodriguez, J.A. The “STK38-XPO1 axis”: its general relevance and mechanistic underpinnings remain to be further characterized. Cell. Mol. Life Sci. 78, 4451–4452 (2021). https://doi.org/10.1007/s00018-021-03778-x

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  • DOI: https://doi.org/10.1007/s00018-021-03778-x

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