Skip to main content

Advertisement

Springer Nature Link
Log in

What tangled webs they weave: Rho-GTPase control of angiogenesis

  • Review
  • Published:
Cellular and Molecular Life Sciences Aims and scope Submit manuscript

Abstract.

The members of the Rho family of small GTPases are involved in an array of cellular processes, including regulation of the actin cytoskeleton, cell polarity, microtubule dynamics, membrane transport, and transcription factor activity. Recent findings have implicated the Rho-proteins as key regulators of angiogenesis, modulating a diversity of cellular processes, including vascular permeability, extracellular matrix remodeling, migration, proliferation, morphogenesis, and survival.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+
from $39.99 /Month
  • Starting from 10 chapters or articles per month
  • Access and download chapters and articles from more than 300k books and 2,500 journals
  • Cancel anytime
View plans

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Explore related subjects

Discover the latest articles, books and news in related subjects, suggested using machine learning.

Author information

Authors and Affiliations

  1. Schepens Eye Research Institute, 20 Staniford Street, Boston, 02114, USA

    B. A. Bryan & P. A. D’Amore

  2. Departments of Ophthalmology and Pathology, Harvard Medical School, Boston, Massachusetts, USA

    B. A. Bryan & P. A. D’Amore

Authors
  1. B. A. Bryan
    View author publications

    Search author on:PubMed Google Scholar

  2. P. A. D’Amore
    View author publications

    Search author on:PubMed Google Scholar

Corresponding author

Correspondence to P. A. D’Amore.

Additional information

Received 8 January 2007; received after revision 21 March 2007; accepted 16 April 2007

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bryan, B.A., D’Amore, P.A. What tangled webs they weave: Rho-GTPase control of angiogenesis. Cell. Mol. Life Sci. 64, 2053–2065 (2007). https://doi.org/10.1007/s00018-007-7008-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00018-007-7008-z

Keywords.