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Nanogoldpharmaceutics
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  • Gold 2006 Scientific Papers
  • Open Access
  • Published: September 2007

Nanogoldpharmaceutics

(i) The use of colloidal gold to treat experimentally-induced arthritis in rat models; (ii) Characterization of the gold in Swarna bhasma, a microparticulate used in traditional Indian medicine

  • Christopher L Brown1,
  • Gillian Bushell1,
  • Michael W Whitehouse1,
  • DS Agrawal2,
  • SG Tupe2,
  • KM Paknikar2 &
  • …
  • Edward RT Tiekink3 

Gold Bulletin volume 40, pages 245–250 (2007)Cite this article

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  • 76 Citations

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Abstract

Nanosized gold particles (27 +/− 3 nm) have been proven to be effective in ameliorating the symptoms of mycobacterial-, collagen- and pristane-induced arthritis in rat models. This contrasts with the drug sodium aurothiomalate that was only effective against mycobacterial-induced arthritis but not to the same extent as Au0. Gold in the traditional Indian Ayurvedic medicine,Swarna bhasma (gold ash), has been characterized as globular particles of gold with an average size of 56–57 nm.

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Authors and Affiliations

  1. Faculty of Science, Griffith University, 4111, Nathan, Queensland, Australia

    Christopher L Brown, Gillian Bushell & Michael W Whitehouse

  2. Microbial Sciences Division, Agharkar Research Institute, 411004, Pune, India

    DS Agrawal, SG Tupe & KM Paknikar

  3. Department of Chemistry, The University of Texas at San Antonio, One UTSA Circle, 78249-0698, San Antonio, Texas, U.S.A.

    Edward RT Tiekink

Authors
  1. Christopher L Brown
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  2. Gillian Bushell
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  6. KM Paknikar
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  7. Edward RT Tiekink
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Open Access This is an open access article distributed under the terms of the Creative Commons Attribution Noncommercial License ( https://creativecommons.org/licenses/by-nc/2.0 ), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

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Brown, C.L., Bushell, G., Whitehouse, M.W. et al. Nanogoldpharmaceutics. Gold Bull 40, 245–250 (2007). https://doi.org/10.1007/BF03215588

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  • Issue Date: September 2007

  • DOI: https://doi.org/10.1007/BF03215588

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Keywords

  • Gold
  • nanoparticle
  • experimental arthritis
  • ayurvedic medicine
  • aurothiomalate
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