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An introduction to the immune network

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Il Nuovo Cimento A (1965-1970)

Summary

In this paper, after a telegraphic introduction to modern immunology, we present a simple model for the idiotypic network among antibodies and we study its relevance for the maintenance of immunological memory. We also consider the problem of computing the memory capacity of such a model.

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References

  1. L. E. Hood, I. L. Weissman, W. B. Wood andJ. H. Wilson:Immunology (Benjamin Publ. Co., Menlo Park, Cal., 1984).

    Google Scholar 

  2. C. Berek andC. Milstein:Immunol. Rev.,105, 5 (1988).

    Article  Google Scholar 

  3. G. Parisi:Ann. Immunol. (Inst. Pasteur),139C, 177 (1988).

    Article  Google Scholar 

  4. Shwartz:Science,248, 374 (1990).

    Google Scholar 

  5. J. Oudin andM. Michel:C. R. Séances Acad. Sci.,257, 805 (1963).

    Google Scholar 

  6. N. K. Jerne: inThe Neurosciences: A Study Program, edited byG. Quarton, T. Melnechuk andF. O. Schmitt (The Rockfeller University Press, New York, N.Y., 1967), pp. 200–208.

    Google Scholar 

  7. N. K. Jerne:Ann. Immunol. (Inst. Pasteur),125C, 1127 (1974).

    Google Scholar 

  8. N. K. Jerne:Immunol. Rev.,79, 5 (1984).

    Article  Google Scholar 

  9. M. Cohn:Ann. Immunol. (Inst. Pasteur),137C, 64 (1986).

    Article  Google Scholar 

  10. D. Holberg, A. Freitas, D. Portnoi, F. Jacquemart, S. Avrameas andA. Coutinho:Immunol. Rev.,93, 147 (1986).

    Article  Google Scholar 

  11. G. W. Hoffmann, T. A. Kion, R. B. Forsyth, K. G. Soga andA. Cooper-Willis: inTheoretical Immunology, edited byA. Perelson (Addison-Wesley, New Jersey, 1988).

    Google Scholar 

  12. F. Rossi, G. Dietrich andM. Kazachzine:Immunol. Rev.,110, 135 (1989).

    Article  Google Scholar 

  13. A. Coutinho:Immunol. Rev.,110, 63 (1989).

    Article  Google Scholar 

  14. F. J. Varela, A. Anderson, G. Dietrich, A. Sumblad, D. Holmberg, M. Kazachzine andA. Coutinho:Proc. Natl. Acad. Sci.,88, 5917 (1991).

    Article  ADS  Google Scholar 

  15. G. Parisi:Phys. Rep.,184, 283 (1989).

    Article  MathSciNet  ADS  Google Scholar 

  16. G. Weisbuch, R. De Boer andA. S. Perelson:J. Theor. Biol.,146, 483 (1990).

    Article  Google Scholar 

  17. P. E. Seiden andF. Celada:J. Theor. Biol,158, 329 (1992).

    Article  Google Scholar 

  18. U. Bern, J. L. van Hemmen andB. J. Sulzer:Theor. Biol.,165, 1 (1993).

    Article  Google Scholar 

  19. G. Parisi:Proc. Natl. Acad. Sci.,87, 429 (1990).

    Article  ADS  Google Scholar 

  20. J. J. Hopfield:Proc. Natl. Acad. Sci. (USA),79, 2554 (1982).

    Article  MathSciNet  ADS  Google Scholar 

  21. A. Cooper-Willis andG. W. Hoffmann:Mol. Immunol.,20, 865 (1983).

    Article  Google Scholar 

  22. K. Rajewsky:Ann. Immunol. (Inst. Pasteur),134D, 133 (1983).

    Article  Google Scholar 

  23. A. Perelson:Theoretical Immunology, SFI Series on the Science of Complexity (Addison Wesley, New Jersey, 1988).

    Google Scholar 

  24. J. Stewart andF. J. Varela:Immunol. Rev.,110, 37 (1989).

    Article  Google Scholar 

  25. M. Mezard, G. Parisi andM. Virasoro:Spin Glass Theory and Beyond (World Scientific, Singapore, 1987).

    MATH  Google Scholar 

  26. O. Lefevre andG. Parisi:Network,4, 39 (1992).

    Article  Google Scholar 

  27. A. Cattaneo: inNeural Networks: from Biology to High Energy Physics, edited byO. Benhar, C. Bosio, P. Del Giudice andE. Tabet (ETS Editrice, Pisa, 1991).

    Google Scholar 

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Parisi, G. An introduction to the immune network. Nuov Cim A 107, 1175–1182 (1994). https://doi.org/10.1007/BF02730864

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