Skip to main content
SpringerLink
Log in

Synthesis of purine derivatives

XVI. The methylation of 2-chlor-7-methylhypoxanthine

  • Published:
Pharmaceutical Chemistry Journal Aims and scope

Abstract

The methylation of 2-chloro-7-methylhypoxanthine in aqueous alkali forms, as well as 2-chloro-1,7-dimethylhypoxanthine, two isomers of this compound. These isomers were isolated and characterized as 2 chloro-3,7-dimethylhypoxanthine and 2 chloro-6-oxo-7, 9-dimethylpurine betaine.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature cited

  1. E. Fischer, Ber. Dtsch. Chem. Ges.,30, 2400 (1897).

    Google Scholar 

  2. L. A. Nikolaeva, M. Ya. Ebed, and E. S. Golovchinskaya, Synthesis of Natural Compounds, Their Analogues and Fragments [in Russian] (1965), Coll. 3, p. 245.

  3. W. Pfleiderer, Justus Liebigs Ann. Chem.,647, 161, 167 (1961).

    Google Scholar 

  4. H. Bredereck, G. Kupsch, and H. Wieland, Ber. Dtsch. Chem. Ges.,92, 566 (1959).

    Google Scholar 

  5. J. W. Jones and R. K. Robins, J. Am. Chem. Soc.,85, 193 (1963).

    Google Scholar 

  6. H. Biltz, Bulow, Justus Liebigs Ann. Chem.,426, 259 (1922).

    Google Scholar 

  7. H. Bredereck, G. Kupsch, and H. Wieland, Ber. Dtsch. Chem. Ges.,92, 583 (1959).

    Google Scholar 

  8. I. M. Ovcharova, L. A. Nikolaeva, E. S. Chaman, et al., Obschch. Khim.,32, 2010 (1962).

    Google Scholar 

  9. I. M. Ovcharova and E. S. Golovchinskaya, Zh. Obshch. Khim.,34, 3247 (1964).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. S. Ordzhonikidze Pharmaceutical Chemistry Research Institute, Moscow

    I. M. Ovcharova & E. S. Golovchinskaya

Authors
  1. I. M. Ovcharova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. S. Golovchinskaya
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 3, pp. 32–37, March, 1967.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ovcharova, I.M., Golovchinskaya, E.S. Synthesis of purine derivatives. Pharm Chem J 1, 146–149 (1967). https://doi.org/10.1007/BF00768573

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00768573

Keywords

Search

Navigation