Summary.
The behaviour of some 2′-phenyl-4R-2,4′-bisthiazoles with respect to electrophilic substitution reactions (halogenation and nitration) has been studied in order to establish relationships between structure and reactivity of the two thiazole rings. The entry of the electrophilic reactants in position 5 or 5′ of the 2,4′-bisthiazole system depends on the nature of the residue in position 4.
Zusammenfassung.
Zur Ermittlung von Zusammenhängen zwischen Struktur und Reaktivität der beiden Thiazolringe wurde das Verhalten einiger 2′-Phenyl-4R-2,4′-bisthiazole bezüglich elektrophiler Substitution (Halogenierung und Nitrierung) untersucht. Der Eintritt der Substituenten in die Positionen 5 bzw. 5′ des Bisthiazolsystems hängt von der Natur des Substituenten in Position 4 ab.
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Received August 24, 1997. Accepted (revised) October 3, 1997
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Oniga, O., Grosu, I., Mager, S. et al. Heterocycles LXXVIII. Electrophilic Substitution of 2′-Phenyl-4R-2,4′-bisthiazoles. Monatshefte fuer Chemie 129, 661–669 (1998). https://doi.org/10.1007/PL00013474
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DOI: https://doi.org/10.1007/PL00013474