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Synthesis and Haemolytic Activity of Randianin Isomers

Synthese und hämolytische Aktivität von Isomeren des Randianins

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Summary.

 Randianin, a haemolytic active saponin from Randia dumetorum, and some of its isomers with different carbohydrate side chains have been synthesized from oleanolic acid. The influence of the linkage within the disaccharide residue on the haemolytic activity of these glycosides has been investigated.

Zusammenfassung.

 Randianin, ein hämolytisches Saponin aus Randia dumetorum, sowie einige dazu isomere Glycoside wurden ausgehend von Oleanolsäure synthetisiert. Der Einfluß der Verknüpfung in der Dissaccharidseitenkette auf die hämolytische Wirkung dieser Glycoside wurde untersucht.

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Authors and Affiliations

  1.  Institute of Pharmaceutical Chemistry, University of Graz, Graz, Austria, AT

    Werner Seebacher, Ernst Haslinger, Armin Presser & Robert Weis

  2.  Institute of Pharmacognosy, University of Vienna, Vienna, Austria, AT

    Karin Rauchensteiner & Johann Jurenitsch

Authors
  1. Werner Seebacher
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  2. Ernst Haslinger
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  3. Karin Rauchensteiner
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  4. Johann Jurenitsch
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  5. Armin Presser
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  6. Robert Weis
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Additional information

Received November 23, 1998. Accepted December 7, 1998

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Seebacher, W., Haslinger, E., Rauchensteiner, K. et al. Synthesis and Haemolytic Activity of Randianin Isomers. Monatshefte fuer Chemie 130, 887–897 (1999). https://doi.org/10.1007/PL00010270

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  • DOI: https://doi.org/10.1007/PL00010270

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