Summary.
Two simple and convenient methods of transforming easily accessible 4-phosphoranylidene-5(4H)-oxazolones into N-acyl-α-triphenylphosphonioglycinates are described. N-Acyl-α-triphenylphosphonioglycinates react smoothly with heteroatom nucleophiles in the presence of DBU or triethylamine yielding the corresponding α-functionalized glycine derivatives.
Zusammenfassung.
Zwei einfache Methoden zur Überführung der leicht zugänglichen 4-Phosphoranyliden-5(4H)-oxazolone in N-Acyl-α-triphenylphosphonionoglycinate werden beschrieben. Die N-Acyl-α-triphenylphosphonionoglycinate reagieren leicht mit Heteroatomnucleophilen in Gegenwart von DBU oder Triethylamin zu den entsprechenden α-funktionalisierten Glycinderivaten.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received June 15, 1998. Accepted (revised) July 21, 1998
Rights and permissions
About this article
Cite this article
Mazurkiewicz, R., Grymel, M. N-Acyl-a-triphenylphosphonioglycinates:A Novel Cationic Glycine Equivalent and its Reactions with Heteroatom Nucleophiles. Monatshefte fuer Chemie 130, 597–604 (1999). https://doi.org/10.1007/PL00010240
Published:
Issue Date:
DOI: https://doi.org/10.1007/PL00010240