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Synthesis of Some New Benzylic Ethers from 1,8-Cineole with Antimicrobial Activity

Synthese einiger neuer Benzylether des 1,8-Cineols mit antimikrobieller Aktivitaüt

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Summary.

 The synthesis and structural characterization of several benzylic derivatives of 3-exo-hydroxy-1,8-cineole is described. The new compounds show antimicrobial activity against Cladosporium cucumerinum, Staphylococcus aureus, Mycobacterium smegmatis, Pseudomonas aeruginosa, and Candida albicans.

Zusammenfassung.

 Die Synthese und strukturelle Charakterisierung einiger Benzylderivate des 3-exo-Hydroxy-1,8-cineols werden beschrieben. Die neuen Verbindungen zeigen antimikrobielle Aktivität gegen Cladosporium cucumerinum, Staphylococcus aureus, Mycobacterium smegmatis, Pseudomonas aeruginosa und Candida albicans.

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Authors and Affiliations

  1.  Department of Chemistry, University of Aveiro, P-3810 Aveiro, Portugal, PT

    Armando J. D. Silvestre & José A. S. Cavaleiro

  2.  Instituto Nacional de Engenharia e Tecnologia Industrial, IBQTA, Laboratório de Microbiologia Industrial, P-1699 Lisboa Codex, Portugal, PT

    Sónia S. Feio & José C. Roseiro

  3.  Institut du Pin, Université de Bordeaux I, F-33405 Talence, France, FR

    Bernard Delmond & Claude Filliatre

Authors
  1. Armando J. D. Silvestre
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  2. José A. S. Cavaleiro
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  3. Sónia S. Feio
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  4. José C. Roseiro
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  5. Bernard Delmond
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  6. Claude Filliatre
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Additional information

Received July 20, 1998. Accepted (revised) September 28, 1998

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Silvestre, A., Cavaleiro, J., Feio, S. et al. Synthesis of Some New Benzylic Ethers from 1,8-Cineole with Antimicrobial Activity. Monatshefte fuer Chemie 130, 589–595 (1999). https://doi.org/10.1007/PL00010239

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  • DOI: https://doi.org/10.1007/PL00010239

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