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Enhanced production of artemisinin by Artemisia annua L hairy root cultures in a modified inner-loop airlift bioreactor

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Abstract

Hairy root cultures of Artemisia annua L were cultured in a modified inner-loop airlift bioreactor for achieving maximum artemisinin production. The effects of initial pH, air flow rate, cycle of light irradiation and temperature on growth and artmisinin production in Artemisia annua L hairy root cultures were investigated. Under the optimum conditions, the maximum production of artemisinin reached to 577.5 mg/l after 20 days.

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Received: 1 December 1997

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Liu, C., Wang, Y., Guo, C. et al. Enhanced production of artemisinin by Artemisia annua L hairy root cultures in a modified inner-loop airlift bioreactor. Bioprocess Engineering 19, 389–392 (1998). https://doi.org/10.1007/PL00009026

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  • DOI: https://doi.org/10.1007/PL00009026

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