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The Clinically Isolated FIZ15 Bacteriophage Causes Lysogenic Conversion in Pseudomonas aeruginosa PAO1

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Abstract.

FIZ15 bacteriophage, from a human clinical isolate of Pseudomonas aeruginosa, causes lysogenic conversion in the P. aeruginosa strain PAO1. The prophage-conferred phenotypes are: (1) increased resistance to phagocytosis by mouse peritoneal macrophages; (2) increased resistance to killing by normal human serum, and (3) increased adhesion to human buccal epithelial cells. These phenotypes are related to the prophage-induced change at the level of its own bacterial receptor, which appears to be the O-antigen.

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Authors and Affiliations

  1. Laboratorio de Genética, Escuela Nacional de Estudios Profesionales Iztacala, Universidad Nacional Autónoma de México, Apartado postal 314, Tlalnepantla, Edo. de Méx., 54090, México , , , , , , MX

    Sergio Vaca-Pacheco, Gloria L. Paniagua-Contreras & Octavio García-González

  2. Departamento de Biología Celular, Centro de Investigación y de Estudios Avanzados del IPN, Apdo. postal 14-740, México D.F. 07000, Mexico , , , , , , MX

    Mireya de la Garza

Authors
  1. Sergio Vaca-Pacheco
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  2. Gloria L. Paniagua-Contreras
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  3. Octavio García-González
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  4. Mireya de la Garza
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Received: 31 August 1998 / Accepted: 20 November 1998

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Vaca-Pacheco, S., Paniagua-Contreras, G., García-González, O. et al. The Clinically Isolated FIZ15 Bacteriophage Causes Lysogenic Conversion in Pseudomonas aeruginosa PAO1. Curr Microbiol 38, 239–243 (1999). https://doi.org/10.1007/PL00006794

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  • DOI: https://doi.org/10.1007/PL00006794

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