Skip to main content
SpringerLink
Log in

A case of Dyke-Davidoff-Masson syndrome associated with central hypothyroidism and secondary adrenal insufficiency

  • Case report
  • Published:
Hormones Aims and scope Submit manuscript

Abstract

A diagnosis of central hypothyroidism (CH) can be missed easily or delayed without a high index of suspicion due to normal or slightly altered thyroid stimulating hormone (TSH) levels during the initial screening test for thyroid dysfunction. A correct diagnosis of CH is very important for safely treating patients. Specifically, doctors must ensure a proper evaluation of combined adrenal insufficiency to prevent a fatal adrenal crisis. Here we report a case of CH combined with secondary adrenal insufficiency in a 42-year-old woman with Dyke-Davidoff-Masson syndrome, which is a rare neurological disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Alexopoulou O, Beguin C, De Nayer P, Maiter D, 2004 Clinical and hormonal characteristics of central hypothyroidism at diagnosis and during follow-up in adult patients. Eur J Endocrinol 150: 1–8.

    Article  PubMed  CAS  Google Scholar 

  2. Grasberger H, Vaxillaire M, Pannain S, et al, 2005 Identification of a locus for nongoitrous congenital hypothyroidism on chromosome 15q25.3-26.1. Hum Genet 118: 348–355.

    Article  PubMed  CAS  Google Scholar 

  3. Atalar MH, Icagasioglu D, Tas F, 2007 Cerebral hemiatrophy (Dyke-Davidoff-Masson syndrome) in childhood: clinicoradiological analysis of 19 cases. Pediatr Int 49: 70–75.

    Article  PubMed  Google Scholar 

  4. Aguiar PH, Liu CW, Leitão H, et al, 1998 MR and CT imaging in the Dyke-Davidoff-Masson syndrome. Report of three cases and contribution to pathogenesis and differential diagnosis. Arq Neuropsiquiatr 56: 803–807.

    Article  PubMed  CAS  Google Scholar 

  5. Zilkha A, 1980 CT of cerebral hemiatrophy. AJR Am J Roentgenol 135:259–262.

    Article  PubMed  CAS  Google Scholar 

  6. Dyke CG, Davidoff LM, Masson CB, 1933 Cerebral hemiatrophy and homolateral hypertrophy of the skull and sinuses. Surg Gynecol Obstet: 588–600.

  7. Ünal O, Tombul T, Cirak B, Anlar O, Incesu L, Kayan M, 2004 Left hemisphere and male sex dominance of cerebral hemiatrophy (Dyke-Davidoff-Masson Syndrome). Clin Imaging 28: 163–165.

    Article  PubMed  Google Scholar 

  8. Hsin YL, Chuang MF, Shen TW, Harnod T, 2011 Tem-poro-spatial analyses define epileptogenic and functional zones in a case of Dyke-Davidoff-Masson syndrome. Seizure 20: 713–716.

    Article  PubMed  CAS  Google Scholar 

  9. Sener RN, Jinkins JR, 1992 MR of craniocerebral hemiatrophy. Clin Imaging 16: 93–97.

    Article  PubMed  CAS  Google Scholar 

  10. Parker CE, Harris N, Mavalwala J, 1972 Dyke-Davidoff-Masson syndrome. Five case studies and deductions from dermatoglyphics. Clinical Pediatrics 11: 288–292.

    Article  PubMed  CAS  Google Scholar 

  11. Stred SE, Byrum CJ, Bove EL, Oliphant M, 1986 Coarctation of the midaortic arch presenting with monoparesis. Ann Thorac Surg 42: 210–212.

    Article  PubMed  CAS  Google Scholar 

  12. Tasdemir HA, Incesu L, Yazicioglu AK, Belet U, Güngör L, 2002 Dyke-Davidoff-Masson syndrome. Clin imaging 26: 13–17.

    Article  PubMed  Google Scholar 

  13. Ono K, Komai K, Ikeda T, 2003 Dyke-Davidoff-Masson syndrome manifested by seizure in late childhood: a case report. J Clin Neurosci 10: 367–371.

    Article  PubMed  Google Scholar 

  14. Devdhar M, Ousman YH, Burman KD, 2007 Hypothyroidism. Endocrinol Metab Clin North Am 36: 595–615.

    Article  PubMed  CAS  Google Scholar 

  15. Faglia G, Bitensky L, Pinchera A, et al, 1979 Thyrotropin secretion in patients with central hypothyroidism: evidence for reduced biological activity of immunoreactive thyrotropin. J Clin Endocrinol Metab 48: 989–998.

    Article  PubMed  CAS  Google Scholar 

  16. Persani L, Ferretti E, Borgato S, Faglia G, Beck Peccoz P, 2000 Circulating thyrotropin bioactivity in sporadic central hypothyroidism. J Clin Endocrinol Metab 85: 3631–3635.

    PubMed  CAS  Google Scholar 

  17. Park SYLM, Kim JH, Kim SY, Shin JY, Shin YG, Chung CH, 2010 A case of dyke-davidoff-masson syndrome associated with hypopituitarism and diabetes mellitus. Korean J Med 79: 316–320.

    Google Scholar 

  18. Benedetti MS, Whomsley R, Baltes E, Tonner F, 2005 Alteration of thyroid hormone homeostasis by antiepileptic drugs in humans: involvement of glucuronosyltransferase induction. Eur J Clin Pharmacol 61: 863–872.

    Article  PubMed  CAS  Google Scholar 

  19. Oppenheimer JH, Fisher LV, Nelson KM, Jailer JW, 1961 Depression of the serum protein-bound iodine level by diphenylhydantion. J Clin Endocrinol Metab 21: 252–262.

    Article  PubMed  CAS  Google Scholar 

  20. Larsen PR, Atkinson AJ, Wellman HN, Goldsmith RE, 1970 The effect of diphenylhydantoin on thyroxine metabolism in man. J Clin Inves 49: 1266–1279.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, South Korea

    Jong Wook Kim, Eun Sook Kim MD, PhD, Eun Young Mo, Sung Dae Moon & Je Ho Han

  2. Department of Neurology, The Catholic University of Korea College of Medicine, Seoul, South Korea

    Woojun Kim & Young Do Kim

  3. Division of Endocrinology, Department of Internal Medicine, Incheon St. Mary’s Hospital, The Catholic University of Korea, 665 Bupyeong 6-dong, Bupyeong-gu, 403-720, Incheon, Korea

    Eun Sook Kim MD, PhD, Eun Young Mo, Sung Dae Moon & Je Ho Han

Authors
  1. Jong Wook Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Eun Sook Kim MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Woojun Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Young Do Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Eun Young Mo
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Sung Dae Moon
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Je Ho Han
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Eun Sook Kim MD, PhD.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kim, J.W., Kim, E.S., Kim, W. et al. A case of Dyke-Davidoff-Masson syndrome associated with central hypothyroidism and secondary adrenal insufficiency. Hormones 12, 461–465 (2013). https://doi.org/10.1007/BF03401312

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03401312

Key words

Search

Navigation