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Effects of Eltoprazine Hydrochloride on Predatory Behavior in Rats

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Abstract

Treatment of rats with the potent antiaggressive compound eltoprazine hydrochloride (1.0 & 2.0 mg/kg) slowed both predatory attack and killing of frogs. These results demonstrate a specific predation-inhibiting action of the drug which is not obscured by the elements of conspecific aggression seen during muricide. Unlike the closely related compound fluprazine, eltoprazine increased both attack and kill latencies implying that the effects of the two drugs on predation are mediated by at least somewhat distinct drug actions. It is further suggested that eltoprazine may be more specifically antiaggressive in its actions than related phenylpiperazine compounds.

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Meek, L.R., Kemble, E.D. Effects of Eltoprazine Hydrochloride on Predatory Behavior in Rats. Psychol Rec 41, 143–146 (1991). https://doi.org/10.1007/BF03395100

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  • DOI: https://doi.org/10.1007/BF03395100

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