Abstract
Drug effects were assessed with a factorial design. Ss were divided into 8 groups for training. Each of 4 groups (D-groups, n=20 ea.) received one dose of drug (5 or 10 mg/kg) at a specified delay before training (10 or 60 min.). The remaining 4 groups ( P-groups,n=20 ea.) received placebo injections. During testing or performance trials (21–40), ½ of each group was maintained under the same drug conditions (D-D and P-P Ss, n=10 ea.). The other ½ was switched to the opposite conditions (D-P and P-D) Ss, n=10 ea.). Analysis revealed that while Ss in the 5 mg/kg. groups were unaffected by GDP, the learning of Ss in the 10 mg/kg groups was greatly retarded, even though CDP at the highest dose did not significantly depress the performance of groups trained under placebo.
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This research presents the results of the junior author’s MA thesis at the University of Delaware. The research was supported by grants HD-00698-03 and MH 07269-02 from the Public Health Service.
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Cicala, G.A., Hartley, D.L. The Effects of Chlordiazepoxide on the Acquisition and Performance of a Conditioned Escape Response in Rats. Psychol Rec 15, 435–440 (1965). https://doi.org/10.1007/BF03393611
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DOI: https://doi.org/10.1007/BF03393611