Several current data indicate that intracranial records of the Bereitschaftspotential from some brain loci manifest baseline shifts (EBS) in the early pre-movement period that are separated from the movement components by a distinct plateau. In this context, main purpose of this study was to assess whether structures generating the EBSs that are simultaneously widespread in various structures of the brain will be specifically linked to higher levels of large-scale integration in comparison to structures that were not involved in EBS generation. In this study were included 21 epilepsy surgery candidates (12 men, 9 women; aged from 18 to 49 years), who were measured during self-paced clenching movements of the hand. Brain activities during the task were recorded using intracerebral electrodes and were evaluated in pairs. Eighty two percent of the EBSs started in various distant brain structures at the same time, eighteen percent at different time. Approximately half of the EBSs of the first group started in the prefrontal regions; the second half was obtained from pairs located in parietal and temporal regions. The first, the second, and the third groups exhibited a special degree of activity synchronization. The simultaneous EBS onsets associated synchronization strongly suggests significantly higher functional coupling of these brain areas which is supposed to be a basic mechanism of integration of various areas of the brain participating in cognitive and intentional functions.
Andersen, R.A., & Cui, H. (2009). Intention, action planning, and decision making in parietalfrontal circuits. Neuron, 63, 568–583.
Ball, T., Schreiber, A., Feige, B., Wagner, M., Lucking, C.H., & Kristeva-Feige, R. (1999). The role of higher-order motor areas in voluntary movement as revealed by high-resolution EEG and fMRI. Neuroimage, 10, 682–694.
Bressler, S.L., & Kelso, J.A.S. (2001). Cortical coordination dynamics and cognition. Trends Cogn Sei (Regul Ed) 5, 26–36.
Burnod, Y., Baraduc, P., Battaglia-Mayer, A., Guigon, E., Koechlin, E., Ferraina, S., Lacquaniti, F., & Caminiti, R. (1999). Parieto-frontal coding of reaching: An integrated framework. Experimental Brain Research 129, 325–46.
Deiber, M.-P., Passingham, R.E., Colebatch, J.G., Friston, K.J., Nixon, P.D., Frackowiak, R.S.J. (1991). Cortical areas and the selection of movement: a study with positron emission tomography. Experimental Brain Research, 84, 393–402.
Deiber, M.-P., Ibanez, V., Sadato, N., & Hallett, M. (1996). Cerebral structures participating in motor preparation in humans: a positron emission tomography study. Journal of Neurophysiology. 75, 233–247.
Deiber, M.-P., Honda, M., Ibanez, V., Sadato, N., & Hallett, M. (1999). Mesial motor areas in self-initiated versus externally triggered movements examined with fMRI: effect of movement type and rate. Journal of Neurophysiology, 81, 3065–77.
Devanne, H. Lavoie, B.A., & Capaday, C. (1997). Input-output properties and gain changes in the human corticospinal pathway. Experimental Brain Research, 114, 329–338.
Dirnberger, G., Durreger, C, Lindinger, G., Lang, W. (2011). On the regularity of preparatory activity preceding movements wit the dominant and nondominant hand: a readiness potential study. International Journal of’Psychophysiology, 81, 127–131.
Fries, P., Reynolds, J.H., Rorie, A.E., & Desimone, R. (2001). Modulation of oscillatory neuronal synchronization by selective visual attention. Science, 291(5508), 1560–3.
Haggard, P. (2011). Decision time for free will. Neuron, 69, 404–406.
Jahanshahi, M., Jenkins, LH., Brown, R.G., Marsden, CD., Passingham, R.E., & Brooks, D.J. (1995). Self-initiated versus externally triggered movements. I. An investigation using measurement of regional cerebral blood flow with PET and movement-related potentials in normal and Parkinson’s disease subjects. Brain, 118, 913–933.
Jahanshahi, M., Hallett, M. (2003). The Bereitschaftspotential. Movement-related cortical potentials. Kluwer Academic/ Plenum Publishers, New York.
Jannerod, M. (1994). The representating brain. Neural correlates of motor intention and imagery. Behavioral and Brain Sciences, 17, 187–245.
Jannerod, M. (2006). The origin of voluntary action. History of a physiological concept. C. R. Biologies, 329, 354–362.
Jannerod, M. (2009). Le cerveau volontaire. Odile Jacob, Paris.
Jenkins, LH., Jueptner, M., Passingham, R.E., & Brooks, DJ. (2000). Self-initiated versus externally triggered movements. II. The effect of movement predictability on regional cerebral blood flow. Brain, 123, 1216–28.
Jensen, O., Kaiser, J., & Lachaux, J., 2007. Human gamma-frequency oscillations associated with attention and memory. Trends in Neurosciences, 30(7), 317–324.
Jonhson, P.B., Ferraina, S., Bianchi, I., & Caminiti, R. (1996). Cortical networks for visual reaching: Physiological and anatomical organization of frontal and parietal lobe arm regions. Cerebral Cortex, 6, 102–119.
Kukleta, M., & Lamarche, M. (2001). Steep early negative slopes can be demonstrated in premovement Bereitschaftspotential. Clinical Neurophysiology, 112, 1642–1649.
Kukleta, M., Bob, P., Brazdil, M., Roman, R., & Rektor, I. (2010). The level of frontal-temporal beta-2 band EEG synchronization distinguishes anterior cingulate cortex from other frontal regions. Consciousness and Cognition, 19, 879–886.
Kukleta, M., Turak, B., & Louvel, J. (2012). Intracerebral recordings of the Bereitschaftspotential demonstrate the heterogeneity of its components. International Journal of Psychophysiology, 83, 65–70.
McKinnon, CD., Capur, S., Hussey, D., Verrier, M.C, Houle, S., Tatton, W.G. (1996). Contribution of the mesial frontal cortex to the premovement potentials associated with intermittent hand movements in humans. Human Brain Mapping, 4, 1–20.
Shibasaki, H., & Hallett, M. (2006). What is the Bereitschaftspotential? Clinical Neurophysiology, 117, 2341–56.
Singer, W. (2001). Consciousness and the binding problem. Annals of the New York Academy of Sciences, 929, 123–46.
Soon, Ch.S., Brass, M., Heinze, H.J., & Haynes, J.D. (2008). Unconscious determinants of free decisions in the human brain. Nature Neuroscience, 11, 543–545.
Talairach, J., Szikla, G., Tournoux, P., Prossalentis, A., Bordas-Ferrer, M., & Covello, L. (1967). Atlas d’Anatomie Stéréotaxique du Télencéphale. Mason, Paris.
Toro, C, Wang, B., Zeffiro, T., Thatcher, R.W., & Hallett, M. (1994). Movement-related cortical potentials: source analysis and PET/MRI correlation. In: Thatcher, R.W., Hallett, M., Zeffiro, T., John, E.R., Huerta, M., editors. Functional Neuroimaging: Technical Foundations. Orlando, FL: Academic Press, pp. 259–267.
Travena, J., & Miller, J. (2002). Cortical movement preparation before and after a conscious decision to move. Consciousness and Cognition, 11, 162–190.
Varela, F., Lachaux, J., Rodrigez, E., & Martinerie, J. (2001). Phase synchronization and largescale integration. Nature Reviews Neuroscience, 2, 229–239.
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Kukleta, M., Bob, P., Turak, B. et al. Large-Scale Synchronization Related to Structures Manifesting Simultaneous EEG Baseline Shifts in the Pre-Movement Period. Act Nerv Super 57, 101–109 (2015). https://doi.org/10.1007/BF03379942
- Intracerebral EEG recordings
- Voluntary movement