Use of Multimodality Imaging and Neuropsychological Measures for the Assessment and Treatment of Auditory Verbal Hallucinations: A Brain to Behavior Approach

Abstract

Patients suffering from auditory verbal hallucinations (AVHs) may utilize unique coping strategies in order to reduce distraction caused by the perception of internal speech. Behavioral strategies may include externalizing speech through self-talk. This paper examines the benefits of a multimodality brain to behavior approach applied to the outpatient psychiatric assessment of a 55-year-old Caucasian female presenting with auditory verbal hallucinations and challenges in attention, concentration, and emotional regulation, who employed self-talk as a coping strategy to focus her attention.

References

  1. Amen, D. G. & Carmichael, B. D. (1997). High resolution brain SPECT imaging in ADHD. Annals of Clinical Psychology, 9(2), 81–86.

    Article  Google Scholar 

  2. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., Text Revision). Washington, DC: Author.

    Google Scholar 

  3. Baerwald, J.P., Tryon, W.W. & Sandford, J. (2001). Modal Attention Asymmetry in Patients with Schizophrenia, Bipolar Disorder, as Compared to Normal Controls. Neuropsychology, 15(4), 535–543.

    Article  PubMed  Google Scholar 

  4. Bentaleb, L., Beauregard, M., Liddle, P., & Stip, E. (2002). Cerebral activity associated with auditory verbal hallucinations: A functional magnetic resonance imaging case study. Journal of Psychiatry & Neuroscience, 27(2), 110–115.

    Google Scholar 

  5. Congedo, M., & Lubar, J. F. (2003). Parametric and non-parametric analysis of QEEG: Normative database comparisons in electroencephalography, a simulation study on accuracy. Journal of Neurotherapy, 7(3–4), 1–29. doi:10.1300/ J184v07n03_01

    Article  Google Scholar 

  6. Dickerson, F., Boronow, J. J., Stallings, C., Origoni, A. E., Cole, S. K., & Yolken, R. H. (2004). Cognitive functioning in schizophrenia and bipolar disorder: Comparison of performance on the Repeatable Battery for the Assessment of Neuropsychological Status. Psychiatry Research, 129(1), 45–53. doi:10.1016/ j.psychres.2004.07.002

    Article  PubMed  Google Scholar 

  7. Ford, J. M., Roach, B. J., Jorgensen, K. W., Turner, J. A., Brown, G. G., Notestine, R. et al. (2009). Tuning in to the voices: A multisite fMRI study of auditory hallucinations. Schizophrenia Bulletin, 35(1), 58–66.

    Article  PubMed  Google Scholar 

  8. Goethals, I., Audenaert, K., Jacobs, F., Van den Eynde, F., Bernagie, K., Kolindou, A., et al. (2005). Brain perfusion SPECT impulsivity-related personality disorders. Behavioral Brain Research, 157(1), 187–192.

    Article  Google Scholar 

  9. Goforth, H. W., Konopka, L., Primeau, M., Ruth, A., O’Donnel, K., Patel, R. et al. (2004). Quantitative electroencephalography in frontotemporal dementia with methylphenidate response: A case study. Clinical EEG and Neuroscience, 35(2), 108–111.

    Article  PubMed  Google Scholar 

  10. Goldenberg, G., Podreka, I., Steiner, M., Franzen, P., & Deecke, L. (1991). Contributions of o ccipital and temporal brain regions to visual and acoustic imagery—A SPECT study. Neuropsychologia, 29(7), 695–702.

    Article  PubMed  Google Scholar 

  11. Hughes, J. R., & John, E. (1999). Conventional and quantitative electroencephalography in psychiatry. The Journal of Neuropsychiatry and Clinical Neurosciences, 11(2), 190–208.

    Article  PubMed  Google Scholar 

  12. Ishii, R., Shinosaki, K., Ikejiri, Y., Ukai, S., Yamashita, K., Iwase, M. et al. (2000). Theta rhythm increases left superior temporal cortex during auditory hallucinations in schizophrenia: A case report. NeuroR eport, 11(14), 3283–3287.

    Article  Google Scholar 

  13. Kane, H. & Whiston, S.C. (2001). Review of the IVA Continuous Performance Test. Buros Fourteenth Mental Measurements Yearbook, 592–595.

    Google Scholar 

  14. Kim, B., Lee, J., Shin, M., Cho, S., & Lee, D. (2002). Regional cerebral perfusion abnormalities in attention deficit/ hyperactivity disorder: Statistical parametric mapping analysis. European Archives of Psychiatry and Clinical Neuroscience, 252(5), 219–225. doi:10.1007/ s00406–002–0384–3

    Article  PubMed  Google Scholar 

  15. Lawrence, A.D. & Sahakian, B.J., Eds. 1996. The neuropsychology of frontostriatal dementias. In: Woods, R.T., Editor, 1996. Handbook of the Clinical Psychology of Aging, Wiley, New York, pp. 243–265.

  16. Lennox, B. R., Park, S. B. G., Medley, I., Morris, P. G., & Jones, P. B. (2000). The functional anatomy of auditory hallucinations in schizophrenia. Psychiatry Research: Neuroimaging 100, 13–20.

    Google Scholar 

  17. Lezak, M. (1995). Neuropsychological assessment (3rd ed.). New York, NY US: Oxford University Press.

    Google Scholar 

  18. Mauri, M. C., Gaietta, M., Dragogna, F., Valli, I., Cerveri, G., & Marotta, G. (2008). Hallucinatory disorder, an original clinical picture’ Clinical and imaging data. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 32, 523–530.

    Article  Google Scholar 

  19. McGuire, P. K., Silbersweig, D. A., & Frith, C. D. (1996). Functional neuroanatomy of verbal self-monitoring. Brain, 119, 907–917.

    Article  PubMed  Google Scholar 

  20. Poprawski, T.J., Pluzyczka, A.N., Park, Y., Chennamchetty, V.N., Halaris, A., Crayton, J.W., Kon poka, L.M. (2007). Multimodality imaging in a depressed patient with violent behavior and temporal lobe seizures. Clinical EEG and Neuroscience, 38 (3), 175–179.

    Article  PubMed  Google Scholar 

  21. Reitan, R. M. & Wolfson, D. (1986). The Halstead-Reitan neuropsychological test battery and aging. Clinical Gerontologist: The Journal of Aging and Mental Health, 5(1–2), 36–61. doi:10.1300/ J018v05n01_03

    Google Scholar 

  22. Robbins, T.W., James, M., Owen, A.M., Sahakian, B.J., McInnes, L. & Rabbitt, P. (1994). Cambridge Neuropsychological Test Automated Battery (CANTAB): A factor analytic study of a large sample of normal elderly volunteers. Dementia, 5, 266–281

    PubMed  Google Scholar 

  23. Spencer, K. M., Niznikiewicz, M. A., Nestor, P. G., Shenton, M. E., & McCarley, R. W. (2009). Left auditory cortex gamma synchronization and auditory hallucination symptoms in schizophrenia. BMC Neuroscience, 10(85), 1–13.

    Google Scholar 

  24. Sweeney, J. A., Kmiec, J. A., and Kupfer, D. J. (2000). Neuropsychologic impairments in bipolar and unipolar mood disorders on the CANTAB neurocognitive battery. Biological psychiatry, 48 (7), 674–684. doi:10.1016/ S0006–3223(00)00910–0

    Article  PubMed  Google Scholar 

  25. Thatcher, R. W., Walker, R. A., Biver, C. J., North, D. N., & Curtin, R. (2003). Quantitative EEG normative database: Validation and clinical correlation. Journal of Neurotherapy, 7 (3–4), 87–121. doi: 10.1300/ J184v07n03_05

    Article  Google Scholar 

  26. Tiijhonen, J., Hari, R., Naukkarinen, H., Rimon, R., Jousmaki, V., & Kajola, M. (1992). Modified activity of the human auditory cortex during auditory hallucinations. American Journal of Psychiatry, 149(2), 255–257.

    Article  Google Scholar 

  27. van de Ven, V. G., Formisano, E., Roder, C. H., Prvulovic, D., Bittner, R. A., Dietz, M. G., et al. (2005). The spatiotemporal pattern of auditory cortical responses during verbal hallucinations. NeuroImage, 27, 644–655.

    Article  PubMed  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Lukasz M. Konopka.

Rights and permissions

Open Access  This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.

The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.

To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Zimmerman, E.M., Golla, M.A., Paciora, R.A. et al. Use of Multimodality Imaging and Neuropsychological Measures for the Assessment and Treatment of Auditory Verbal Hallucinations: A Brain to Behavior Approach. Act Nerv Super 53, 150–158 (2011). https://doi.org/10.1007/BF03379939

Download citation

Key words

  • EEG
  • hallucinations
  • LORETA
  • SPECT
  • Neuropsychology