Summary
This paper describes a comprehensive profitability analysis of late mover products in a large segment of the global market for cardiovascular drugs. The study is based on the estimation and classification of over 200 product life cycles from four global cardiovascular product categories which leads to different life cycles for the pioneer as well as early follower products on the one hand and late mover products on the other hand. The order of entry, thus, is not only crucial to achieve a certain market share level but also to the shape of the drug life cycle and finally for the long term economic evaluation of innovative products. The paper provides first findings on this subject through a simulation study which is in line with previous research designs and shows the impact of the product life cycle shape on the net present value. The effects of relative changes in several input values on net present value are investigated in a sensitivity analysis. The computation of selected point elasticities reveals the potential impact decisions on marketing mix variables like price and promotional effort can have.
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Literaturverzeichnis
Baber, W. R./ Kang, S.-H. (1996): Estimates of Economic Rates of Return for the U.S. Phamaceutical Industry, 1976–1987, in: Journal of Accounting and Public Policy, 15, S. 327–346.
Bauer, H. H./ Fischer, M. (2000): Die empirische Typologisierung von Produktlebenszyklen und ihre Erklärung durch die Markteintrittsreihenfolge, in: Zeitschrift für Betriebswirtschaft, 70, S. 937–958.
Bauer, H. H./ Fischer, M./ Verspagen, R. (1999): Determinanten des ‘Line Extension’-Erfolgs, Ergebnisse einer empirischen Studie, in: Die Pharmazeutische Industrie, 61, S. 796–803.
Berndt, E./ Bui, L. T./ Reiley, D. H./ Urban, G. L. (1994): The Roles of Marketing, Product Quality, and Price Competition in the Growth and Composition of the U.S. Anti-Ulcer Drug Industry, Working Paper #19-94, Sloan School, MIT.
Bierly, P./ Chakrabarti, A. (1996): Determinants of Technology Cycle Time in the U.S. Pharmaceutical Industry, in: R&D Management, 26, S. 115–126.
Bond, R. S./ Lean, D. F. (1977): Sales Promotion and Product Differentiation in Two Prescription Drug Markets, Federal Trade Commission, Washington DC.
Bowman, D./ Gatignon, H. (1996): Order of Entry as a Moderator of the Effect of the Marketing Mix on Market Share, in: Marketing Science, 15, S. 222–242.
Buzzell, R. D./Gale, B. T. (1989): Das PIMS-Programm: Strategien und Unternehmenserfolg.
DiMasi, J. A. (1995): Success Rates for New Drugs Entering Clinical Testing in the United States, in: Clinical Pharmacology & Therapeutics, 58, S. 1–14.
DiMasi, J. A./ Grabowski, H. G./ Vernon, J. M. (1995): R&D Costs, Innovative Output and Firm Size in the Pharmaceutical Industry, in: International Journal of the Economics of Business, 2, S. 201–219.
DiMasi, J. A./ Hansen, R. W./ Grabowski, H. G./ Lasagna, L. (1995): Research and Development Costs for New Drugs by Therapeutic Category, in: PharmacoEconomics, 7, S. 152–169.
DiMasi, J. A./ Hansen, R. W./ Grabowski, H. G./ Lasagna, L. (1991): Cost of Innovation in the Pharmaceutical Industry, in: Journal of Health Economics, 10, S. 107–142.
Grabowski, H. G./ Vernon, J. (1994): Returns to R&D on New Drug Introductions in the 1980s, in: Journal of Health Economics, 13, S. 384–406.
Grabowski, H. G./ Vernon, J. (1990): A New Look at the Returns and Risks to Pharmaceutical R&D, in: Management Science, 36, S. 804–821.
Grabowski, H. G./ Vernon, J. (1982): A Sensitivity Analysis of Expected Profitability of Pharmaceutical Research and Development, in: Managerial and Decision Economics, 3, S. 36–40.
Graves, S. B./ Langowitz, N. S. (1993): Innovative Productivity and Returns to Scale in the Pharmaceutical Industry, in: Strategic Management Journal, 14, S. 593–605.
Jensen, E. J. (1987): Research Expenditures and the Discovery of New Drugs, in: Journal of Industrial Economics, 36, S. 83–95.
Joglekar, P./ Patterson, M. L. (1986): A Closer Look at the Returns and Risks of Pharmaceutical R&D, in: Journal of Health Economics, 5, S. 153–177.
Kalyanaram, G./ Robinson, W. T./ Urban, G. L. (1995): Order of Market Entry: Established Empirical Generalizations, Emerging Empirical Generalizations, and Future Research, in: Marketing Science, 14, part 2 of No. 3, G212–G221.
Mansfield, E. (1987): Price Indexes for R and D Inputs, 1969–1983, in: Management Science, 33, S. 124–129.
Mattison, N./ Trimble, A. G./ Lasagna, L. (1988): New Drug Development in the United States, 1963–1984, in: Clinical Pharmacology & Therapeutics, 43, S. 15–27.
Myers, S. C./ Howe, C. D. (1997): A Life Cycle Financial Model of Pharmaceutical R&D, Working Paper #41-97, MIT.
Myers, S. C./ Shyam-Sunder, L. (1996): Cost of Capital Estimates for Pharmaceutical Research and Development, in: Helms, R. D. (ed.): Competitive Strategies in the Pharmaceutical Industry, American Enterprise Institute, Washington, DC.
OTA; U.S. Congress, Office of Technology Assessment (1993): Pharmaceutical R&D: Costs, Risks, and Rewards, Washington, U.S. Government Printing Office.
Robinson, W. T./ Kalyanaram, G./ Urban, G. L. (1994): First-Mover Advantages from Pioneering New Markets: A Survey of Empirical Evidence, in: Review of Industrial Organization, 9, S. 1–23.
Sheck, L./ Cox, C./ Davis, H. T./ Trimble, A. G./ Wardell, W. M./ Hansen, R. W. (1984): Success Rates in the United States Drug Development System, in: Clinical Pharmacology & Therapeutics, 36, S. 574–583.
Szymanski, D. M./ Troy, L. C./ Bharadwaj, S. J. (1995): Order of Entry and Business Performance: An Empirical Synthesis and Reexamination, in: Journal of Marketing, 59 (Winter), S. 17–33.
Urban, G. L./ Carter, T./ Gaskin, S./ Mucha, Z. (1986), Market Share Rewards to Pioneering Brands: An Empirical Analysis and Strategic Implications, in: Management Science, 32, S. 645–695.
Wiggins, S. (1987): The Cost of Developing a New Drug, Pharmaceutical Manufacturers Association, Washington, DC.
Woltman, H. R. (1989): Reviewing the Bidding: R&D Costs and Profitybility of New Chemical Entities, in: Journal of Research in Pharmaceutical Economics, 1, S. 49–65.
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Bauer, H.H., Fischer, M. & Pfahlert, V. Lohnt sich für Pharmaunternehmen der Markteintritt als Late Mover? — Ergebnisse einer Rentabilitätsanalyse. Schmalenbachs Z betriebswirtsch Forsch 53, 632–648 (2001). https://doi.org/10.1007/BF03372662
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DOI: https://doi.org/10.1007/BF03372662