Skip to main content
Log in

Role of ras and gsp oncogenes in human epithelial thyroid tumorigenesis

  • Published:
Journal of Endocrinological Investigation Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Lemoine N.R., Mayall E.S., Wyllie F.S., Farr C.J., Hughes D., Padua R.A., Thurston V., Williams E.D., Wynford-Thomas D. Activated ras oncogenes in human thyroid cancers. Cancer Res. 48: 4459, 1988.

    PubMed  CAS  Google Scholar 

  2. Lemoine N.R., Mayall E.S., Wyllie F.S., Williams E.D., Goyns M., Stringer B., Wynford-Thomas D. High frequence of ras oncogene activation in all stages of human thyroid tumorigenesis. Oncogene 4: 159, 1989.

    PubMed  CAS  Google Scholar 

  3. Suarez H.G., Du Villard J.A., Caillou B., Schlumberger M., Tubiana M., Parmentier C., Monier R. Detection of activated ras oncogenes in human thyroid carcinomas. Oncogene 2: 403, 1988.

    PubMed  CAS  Google Scholar 

  4. Suarez H.G., Du Villard J.A., Severino M., Caillou B., Schlumberger M., Tubiana M., Parmentier C., Monier R. Presence of mutations in all three ras genes in human thyroid tumors. Oncogene 5: 565, 1990.

    PubMed  CAS  Google Scholar 

  5. Lyons J., Landis C.A., Harsh G., Vallar L., Grunewald K., Feichtinger H., Duh Q.Y., Clark O.H., Kawasaki E., Bourne H.R., McCormick F. Two G protein oncogenes in human endocrine tumors. Science 249: 655, 1990.

    Article  PubMed  CAS  Google Scholar 

  6. Suarez H.G., Du Villard J.A., Caillou B., Schlumberger M., Parmentier C, Monier R. Gsp mutations in human thyroid tumors. Oncogene 6: 677, 1991.

    PubMed  CAS  Google Scholar 

  7. Allard M.W., Ellsworth D.L., Honeycut R.L. The production of single-stranded DNA suitable for sequencing using the polymerase chain reaction. Biotechniques 10: 24, 1991

    PubMed  CAS  Google Scholar 

  8. Wynford-Thomas D. Origine et progression des tumeurs épithéliales: vers les mécanismes cellulaires et moléculaires. Medecine/Sciences 9: 66, 1993.

    Article  Google Scholar 

  9. Bos J.L., Fearon E.R., Hamilton S.R., Verlaan de Vries M., vanBoom J.H., van der Eb A.J., Vogelstein B. Prevalence of ras gene mutations in human colorectal cancers. Nature 327: 293, 1987.

    Article  PubMed  CAS  Google Scholar 

  10. Namba H., Rubin S., Fagin J.A. Point mutations of ras oncogenes are an early event in thyroid tumorigenesis. Mol. Endocrinol. 4: 1474, 1990.

    Article  PubMed  CAS  Google Scholar 

  11. Yoshimoto K., Iwahana H., Fukuda A., Sano T., Itakura M. Rare mutations of the Gs alpha subunit gene in human endocrine tumors. Cancer 72: 1386, 1993.

    Article  PubMed  CAS  Google Scholar 

  12. O’Sullivan C.O., Barton C.M., Staddon S.L., Brown C.L., Lemoine N.R. Activating point mutations of the gsp oncogene in human thyroid adenomas. Mol. Carcinog. 4: 345, 1991.

    Article  PubMed  Google Scholar 

  13. Lemoine N.R., Mayall E.S., Williams E.D., Thurston V., Wynford-Thomas D. Agent specific ras oncogene activation in rat thyroid tumors. Oncogene 3: 541, 1988.

    PubMed  CAS  Google Scholar 

  14. Wright P., Williams E.D., Lemoine N.R., Wynford-Thomas D. Radiation associated and “spontaneous” human thyroid carcinomas show a different pattern of ras oncogene mutation. Oncogene 6: 471, 1991.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Du Villard, J.A., Schlumberger, M., Wicker, R. et al. Role of ras and gsp oncogenes in human epithelial thyroid tumorigenesis. J Endocrinol Invest 18, 124–126 (1995). https://doi.org/10.1007/BF03349719

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03349719

Key-words

Navigation