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Augmentation of prolactin response to TRH after cyproheptadine

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Abstract

Serum PRL, TSH, T3 and T4 were estimated in the basal state and following iv bolus injection of 100 μg synthetic thyrotropin releasing hormone before and 7 days after cyproheptadine treatment in 5 healthy adult males. Only the PRL response to TRH was augmented after cyproheptadine. This is perhaps related to the antidopaminergic effect of cyproheptadine.

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Authors and Affiliations

  1. Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India

    A. C. Ammini, R. J. Dash M.D. (Associate Professor and Acting Head) & R. Sialy

Authors
  1. A. C. Ammini
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  2. R. J. Dash M.D.
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  3. R. Sialy
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Ammini, A.C., Dash, R.J. & Sialy, R. Augmentation of prolactin response to TRH after cyproheptadine. J Endocrinol Invest 4, 99–101 (1981). https://doi.org/10.1007/BF03349424

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  • DOI: https://doi.org/10.1007/BF03349424

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