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Isolated growth hormone deficiency after severe head trauma

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Abstract

In a 12-yr-old boy growth arrest occurred after severe head trauma. Evaluation of pituitary endocrine function revealed isolated growth hormone (GH) deficiency. Lack of GH response to GH-releasing factor indicated that the responsible lesion was most likely to be localized in the pituitary gland. GH substitution resulted in biochemical (somatomedin increase) and clinical (catch up growth) response.

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Eichler, I., Frisch, H., Eichler, H.G. et al. Isolated growth hormone deficiency after severe head trauma. J Endocrinol Invest 11, 409–411 (1988). https://doi.org/10.1007/BF03349069

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