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Association of multinodular goiter with breast carcinoma: Cowden’s disease1

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Abstract

Cowden’s Disease or multiple hamartoma syndrome is an autosomal dominant genodermatosis associated with abnormalities of the breast, thyroid gland, gastrointestinal tract and genitourinary system. A large percentage of these patients have goiters or other thyroid abnormalities. Physicians should consider the diagnosis of Cowden’s disease in patients presenting with thyroid disease and skin lesions such as papules or skin tags and if present these subjects should be screened for other malignancies associated with this disease.

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Authors and Affiliations

  1. Department of Medicine, Uniformed Services University of the Health Sciences, USA

    R. D. Michaels &  K. M. M. Shakir M.C., USN

  2. Division of Endocrinology and Metabolism, Department of Internal Medicine, National Naval Medical Center, Bethesda, Maryland, USA

    R. D. Michaels &  K. M. M. Shakir M.C., USN

Authors
  1. R. D. Michaels
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  2. K. M. M. Shakir M.C., USN
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The opinions and assertions contained herein are the private ones of the authors and are not to be constructed as official or as reflecting the views of the Navy Department or the Naval Service at large.

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Michaels, R.D., Shakir, K.M.M. Association of multinodular goiter with breast carcinoma: Cowden’s disease1. J Endocrinol Invest 16, 909–911 (1993). https://doi.org/10.1007/BF03348956

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  • DOI: https://doi.org/10.1007/BF03348956

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