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Bone histomorphometry in Cushing’s syndrome

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Abstract

Bone involvement is a common finding in Cushing’s syndrome. The actions of corticosteroids on bone have been studied quite intensively but only a few studies of bone histomorphometry in this syndrome have been published. In this paper we present histomorphometric measurements of bone activity in 7 patients with a postoperative reevaluation in two. The results show irregular alterations on histomorphometric parameters with an increased bone resorption and decreased bone formation rate. After surgery the abnormalities changed towards normal.

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Authors and Affiliations

  1. Endocrine Service, 1st Medical Clínics Hospital das Clinicas, University of São Paulo, Brazil

    Aurelio Borelli MD & V. Jorgetti

  2. Laboratory of Human Nutrition and Metabolic Diseases São Paulo, SP, Brazil

    M. O. Ribeiro Leite, P. H. S. Correa, J. A. M. Marcondes, J. R. F. Batalha, A. B. Ulhõa Cintra & B. L. Wajchenberg

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  1. Aurelio Borelli MD
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  2. M. O. Ribeiro Leite
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  3. P. H. S. Correa
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  4. V. Jorgetti
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  5. J. A. M. Marcondes
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  6. J. R. F. Batalha
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  7. A. B. Ulhõa Cintra
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  8. B. L. Wajchenberg
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Borelli, A., Leite, M.O.R., Correa, P.H.S. et al. Bone histomorphometry in Cushing’s syndrome. J Endocrinol Invest 15, 783–787 (1992). https://doi.org/10.1007/BF03348804

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  • DOI: https://doi.org/10.1007/BF03348804

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