Abstract
The aim of this study was to ascertain whether there was an interrelationship between male osteoporosis, calcitonin and androgens. Ten young hypogonadal osteoporotic men were studied: testosterone and calcitonin plasma levels were measured before and after therapy with testosterone enanthate (200 mg im every three weeks for four months). In these patients testosterone and calcitonin plasma levels were significantly lower than controls, before therapy (p < 0.001 and p < 0.01 respectively). Testosterone treatment significantly increased (p < 0.05) serum calcitonin. The conclusion was that androgen deficiency may cause osteoporosis also by decreasing calcitonin secretion.
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References
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Foresta, C., Zanatta, G.P., Busnardo, B. et al. Testosterone and calcitonin plasma levels in hypogonadal osteoporotic young men. J Endocrinol Invest 8, 377–379 (1985). https://doi.org/10.1007/BF03348518
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DOI: https://doi.org/10.1007/BF03348518