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Pseudotumor cerebri and thyroid-replacement therapy in patients affected by differentiated thyroid carcinoma

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Abstract

The pseudotumor cerebri, a neurological syndrome clinically characterized by headaches, vomiting and bilateral papilledema, occurred in two patients, previously subjected to total thyroidectomy for differentiated thyroid carcinoma, after initiation of levothyroxine replacement therapy. In patients with thyroid cancer, subjected to thyroidectomy and then thyroid hormone replacement therapy, the possible development of pseudotumor cerebri syndrome should be considered and differentiated from CNS symptoms due to brain metastases.

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References

  1. Sugar O Central neurological complications of hypoparathyroidism. Arch. Neurol. Psychiatry 70: 86, 1953.

    Article  CAS  Google Scholar 

  2. Dees S.C., McKay H.W. Jr. Occurrence of pseudotumor cerebri (benign intracranial hypertension) during treatment of children with asthma by adrenal steroids: report of three cases. Pediatrics 23: 1143, 1959.

    CAS  PubMed  Google Scholar 

  3. Walker A.E., Adamkiewicz J.J. Pseudotumor cerebri associated with prolonged corticosteroid therapy: reports of four cases. JAMA 188: 779, 1964.

    CAS  PubMed  Google Scholar 

  4. Neville B.G.R., Wilson J. Benign intracranial hypertension following corticosteroid withdrawal in childhood. Br. Med. J. 3: 554, 1970.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  5. Van Wyck J.J., Grumbach M.M. Syndrome of precocious menstruation in juvenile hypothyroidism: an example of hormonal overlap in pituitary feed-back. J. Pediatr. 57: 416, 1960.

    Article  Google Scholar 

  6. Van Dop C., Conte F.A., Koch T.K., Clark S.J., Wilson-Davis S.L., Grumbach M.M. Pseudotumor cerebri associated with initiation of levothyroxine therapy for juvenile hypothyroidism. N. Engl. J. Med. 308: 1076, 1983.

    Article  PubMed  Google Scholar 

  7. Prendes J.L., McLean W.T. Jr. Pseudotumor cerebri during treatment for hypothyroidism. South Med. J. 71: 977, 1978.

    Article  CAS  PubMed  Google Scholar 

  8. Panza N., De Rosa M., Lombardi G., Salvatore M. Serum thyroglobulin in patients with early thyroid cancer who have residual thyroid tissue after total thyroidectomy. Lancet 1: 398, 1984.

    Article  CAS  PubMed  Google Scholar 

  9. Schlumberger M., Fragu P., Parmentier C., Tubiana M. Thyroglobulin assay in the follow-up of patients with differentiated thyroid carcinomas: comparison of its value in patients with or without normal residual tissue. Acta Endocrinol. (Kbh.) 98: 215, 1981.

    CAS  Google Scholar 

  10. Panza N., Lombardi G., Minozzi M., Salvatore M., Claudio F., Mariano A., Macchia V. [131]-total body scan and serum thyroglobulin assay in the follow-up of surgically treated patients affected by differentiated thyroid carcinoma. J. Nucl. Med. All. Sci. 28: 9, 1984.

    CAS  Google Scholar 

  11. Van Herle A.J., Viller R.P. Elevated serum thyroglobulin. A marker of metastases in differentiated thyroid carcinoma. J.Clin. Invest. 56: 272, 1975.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  12. Pacini F., Pinchera A., Grassi C., Grasso L., Doveri F., Baschieri L. Serum thyroglobulin in thyroid carcinoma and other thyroid disorders. J. Endocrinol. Invest. 3: 283, 1980.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Istituto di Scienze Endocrinologiche, II Facoltà di Medicina e Chirurgia, Università di Napoli, 80100, Napoli, Italy

    N. Panza, M. De Rosa &  Gaetano Lombardi

  2. Istituto di Scienze Radiologiche, II Facoltà di Medicina e Chirurgia, Università di Napoli, 80100, Napoli, Italy

    M. Salvatore

Authors
  1. N. Panza
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  2. M. De Rosa
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  3. Gaetano Lombardi
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  4. M. Salvatore
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Panza, N., De Rosa, M., Lombardi, G. et al. Pseudotumor cerebri and thyroid-replacement therapy in patients affected by differentiated thyroid carcinoma. J Endocrinol Invest 8, 357–358 (1985). https://doi.org/10.1007/BF03348513

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  • DOI: https://doi.org/10.1007/BF03348513

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