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Colloid droplet accumulation precedes the enhancement of 6-keto-PGF 1 α release from the thyrotropin-stimulated thyroid gland

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Abstract

Influence of thyrotropin (TSH) on colloid droplet formation in thyroid follicular cells and on release of a stable prostacyclin metabolite, 6-keto-prostaglandin 1 α (6-keto-PGF 1α) from the thyroid has been studied in rats. Maximal accumulation of colloid droplets preceded the enhancement of the 6-keto-PGF 1 α release. Such a time sequence speaks against the possibility of prostacyclin involvement in the thyroid secretory response to TSH.

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Pawlikowski, M., Lewinski, A., Kunert-Radek, J. et al. Colloid droplet accumulation precedes the enhancement of 6-keto-PGF 1 α release from the thyrotropin-stimulated thyroid gland. J Endocrinol Invest 8, 293–295 (1985). https://doi.org/10.1007/BF03348499

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  • DOI: https://doi.org/10.1007/BF03348499

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