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False-positive diagnosis of adrenal pheochromocytoma on iodine-123-MIBG scan

Journal of Endocrinological Investigation volume 21, pages 779–783 (1998)Cite this article

Abstract

I-123 metaiodobenzylguanidine (I-123 MIBG) scintigraphy is known for its high specificity in detecting pheochromocytoma and other tumors of neural crest origin. In this rare case report, we describe a definite adrenocortical adenoma that demonstrated false-positive uptake at I-123 MIBG scintigraphy and a remarkable accumulation of 75-SE-6-beta-selenomethyl-norcholesterol.

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Affiliations

  1. Istituto di 2a Clinica Medica, Rome, Italy

    Claudio Letizia M.D., C. Caliumi, S. Subioli & E. D’Erasmo

  2. Istituto di 1a Clinica Chirurgica, Rome, Italy

    G. De Toma

  3. Istituto di Radiologia, Parma, Italy

    R. Massa

  4. Dipartimento di Medicina Sperimentale-Anatomia Patologica, Università degli Studi di Roma, “La Sapienza”, Rome, Italy

    A. Corsi

Authors
  1. Claudio Letizia M.D.
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  2. G. De Toma
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  3. R. Massa
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  4. A. Corsi
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  5. C. Caliumi
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  6. S. Subioli
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  7. E. D’Erasmo
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Letizia, C., De Toma, G., Massa, R. et al. False-positive diagnosis of adrenal pheochromocytoma on iodine-123-MIBG scan. J Endocrinol Invest 21, 779–783 (1998). https://doi.org/10.1007/BF03348046

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Key-words

  • I-123 metaiodobenzylguanidine scintigraphy
  • false-positive result
  • adrenocortical adenoma