Skip to main content
SpringerLink
Log in

Growth hormone deficiency throughout puberty

  • Review Article
  • Published:
Journal of Endocrinological Investigation Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Frasier S.D., Costin G., Lippe B.M., Aceto T., Bunger P.F. Dose response curve for human growth hormone. J. Clin. Endocrinol. Metab. 53: 1213, 1981.

    Article  CAS  PubMed  Google Scholar 

  2. Albertsson-Wikland K., Westphal O., Westgren U. Daily subcutaneous administration of human growth hormone in growth hormone deficient children. Acta Paediatr. Scand. 75:89, 1986.

    Article  CAS  PubMed  Google Scholar 

  3. Hindmarsh P.C., Stanhope R., Preece M.A., Brook C.G.D. Frequency of administration of growth hormone — an important factor in determining growth response to exogenous growth hormone. Hormone Res. 33(suppl 4): 83, 1990.

    Article  PubMed  Google Scholar 

  4. Brook C.G.D., Hindmarsh P.C., Stanhope R. Growth and growth hormone secretion: a review. J. Endocrinol. 119:179, 1988.

    Article  CAS  PubMed  Google Scholar 

  5. Stanhope R., Pringle P.J., Brook C.G.D. The mechanism of the adolescent growth spurt induced by low-dose pulsatile GnRH treatment. Clin. Endocrinol. 28:83, 1988.

    Article  CAS  Google Scholar 

  6. Stanhope R., Brook C.G. The clinical diagnosis of disorders of puberty: the loss of consonance. Br. J. Hosp. Med. 35:57, 1986.

    CAS  PubMed  Google Scholar 

  7. Marshall W.A., Tanner J.M. Variations in the pattern of pubertal changes in girls Arch. Dis. Child. 44:291, 1969.

    Article  CAS  Google Scholar 

  8. Marshall W.A., Tanner J.M. Variations in the pattern of pubertal changes in boys Arch. Dis. Child. 45:13, 1970.

    Article  CAS  Google Scholar 

  9. Stanhope R., Brook C.G.D., Pringle P.J., Adams J., Jacobs H.S. Induction of puberty by pulsatile gonadotrophin releasing hormone. Lancet ii: 552, 1987.

    Article  Google Scholar 

  10. Mauras N., Blizzard R.M., Link K., Johnson M.L., Rogol A.D., Veldhuis J.D. Augmentation of growth hormone secretion during puberty: evidence for a pulse amplitude-modulated phenomenon. J. Clin. Endocrinol. Metab. 64: 596, 1987.

    Article  CAS  PubMed  Google Scholar 

  11. Drop S.L., Sabbe-Claus L., Visser H.K.A. The effect of puberty and short-term oral administration of testosterone undecanoate on GH tests and sex steroid related plasma compounds in GH deficient patients. Clin. Endocrinol. 76:375, 1982.

    Article  Google Scholar 

  12. Davoren J.B., Hsueh J. W. Growth hormone increases ovarian levels of immunoreactive somatomedin C/insulin-like growth factor I in vivo. Endocrinology 78:888, 1986.

    Article  Google Scholar 

  13. Tres L.L., Smith E., Van Wyk J.J., Kierszenbaum A.L. Somatomedin-C in rat Sertoli-spermatogenic cell cocultures. J. Cell. Biol. 97:18a, 1983.

    Google Scholar 

  14. Adashi E.Y., Resnick C.E., D’Ercole A.J., Svoboda M.E., Van Wyk J.J. Insulin-like growth factors as intraovarian regulators of granulosa cell growth and function. Endocr. Rev. 6:400, 1985.

    Article  CAS  PubMed  Google Scholar 

  15. Homburg R., Eshel A., Abdalla H.I., Jacobs H.S. Growth hormone facilitates ovulation induction by gonadotrophins. Clin. Endocrinol. 29:113, 1988.

    Article  CAS  Google Scholar 

  16. Aynsley-Green A., Zachmann M., Prader A. Inter-relation of the therapeutic effects of growth hormone and testosterone on growth in hypopituitarism. J. Pediatr. 89:992, 1976.

    Article  CAS  PubMed  Google Scholar 

  17. Van der Werff ten Bosch J.J., Bot A. Does hGH treatment promote adult height of hypopituitary children? J. Med. 32:217, 1988.

    Google Scholar 

  18. Zachmann M., Prader A. Anabolic and androgenic effect of testosterone in sexually immature boys and its dependency on growth hormone. J. Clin. Endocrinol. Metab. 30:85, 1970.

    Article  CAS  PubMed  Google Scholar 

  19. Price D.A., Shalet S.M., Clayton P.E. Management of idiopathic growth hormone deficient patients during puberty. Acta Paediatr. Scand. (suppl) 347:44, 1988.

    CAS  Google Scholar 

  20. Burns E.C., Tanner J.M., Preece M.A., Cameron N. Final height and pubertal development in 55 children with idiopathic growth hormone deficiency treated for between 2 and 15 years with human growth hormone. Eur. J. Paediatr. 737:155, 1981.

    Google Scholar 

  21. Bourguignon J.P., Vandewegh M., Vanderschueren-Lodeweycx M., Malvaux P., Wolter R., Du Caju M., Ernould C. Pubertal growth and final height in hypopituitary boys: a minor role of bone age at onset of puberty. J. Clin. Endocrinol. Metab. 63:376, 1986.

    Article  CAS  PubMed  Google Scholar 

  22. Hibi I., Tanaka T. Final height of patients with idiopathic growth hormone deficiency after long-term growth hormone treatment. Acta Endocrinol. 120:409, 1989.

    Article  CAS  PubMed  Google Scholar 

  23. Darendeliler F., Hindmarsh P.C., Preece M.A., Cox L., Brook C.G D. Growth hormone increases rate of pubertal maturation. Acta Endocrinol. 722:414, 1990.

    Google Scholar 

  24. Vanderschueren-Lodeweyckx M., van den Broeck J., Wolter R., Malvaux P. Early initiation of growth hormone treatment: influence on final height. Acta Paediatr. Scand. (suppl.) 337: 4, 1987.

    Article  CAS  Google Scholar 

  25. Stanhope R., Uruena M., Hindmarsh P., Leiper A.D., Brook C.G.D. Management of growth hormone deficiency through puberty. Acta Paediatr. Scand. (suppl.) 372:47, 1991.

    Article  CAS  Google Scholar 

  26. Stanhope R., Albanese A., Hindmarsh P.C., Brook C.G.D. The effects of growth hormone therapy on spontaneous sexual development. Hormone Res. (in press), 1992.

    Google Scholar 

  27. Job J.C., Chaussain J-L., Gamier P., Rolland A., Joab N. Dose-response relationship in the treatment of hypopituitary children with human growth hormone: a retrospective survey. Acta Paediatr. Scand. (suppl.) 337: 93, 1987.

    Article  CAS  Google Scholar 

  28. Toublanc J.E., Couprie C., Gamier P., Job J.C. The effects of treatment combining an agonist of gonadotrophin-releasing hormone with growth hormone in pubertal patients with isolated growth hormone deficiency. Acta Endocrinol. 720:795, 1989.

    Google Scholar 

  29. Hibi I., Takana T., Tanae A., Kagawa J., Hashimoto N., Yoshizawa A., Shizume K. The influence of gonadal function and the effect of gonadal suppression treatment on final height in growth hormone (GH) treated GH deficient children. J. Clin. Endocrinol. Metab. 69:221, 1989.

    Article  CAS  PubMed  Google Scholar 

  30. Stanhope R., Papadimitriou A., Chessells J.M., Leiper A.D. Precocious and premature puberty following prophylactic irradiation in acute lymphoblastic leukaemia. In: Green D. (Ed.), Late effects of treatment for childhood cancer. Wiley-Liss Inc, New York, 1992, p. 89.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Medical Unit, The Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK

    A. Albanese &  R. Stanhope

Authors
  1. A. Albanese
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Stanhope
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Albanese, A., Stanhope, R. Growth hormone deficiency throughout puberty. J Endocrinol Invest 15, 777–781 (1992). https://doi.org/10.1007/BF03347651

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03347651

Key-words

Search

Navigation