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Spontaneous short-term remission of primary hyperparathyroidism from infarction of a parathyroid adenoma

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Abstract

We report a 39-yr-old woman with spontaneous short-term remission of primary hyperparathyroidism (PHPT). She was referred to our Department for PHPT with bilateral kidney stones diagnosed elsewhere; at the time of our observation she had developed anterior neck pain associated with swelling and tenderness. Biochemical data (serum ionized calcium and PTH) suggested a remission of the PHPT. The local symptoms gradually improved and disappeared over the next several days without therapy. Serum ionized calcium and PTH levels remained normal for up to 11 months. Subsequently, the patient had a recurrence of PHPT with mild hypercalcemia and elevated PTH levels. The patient underwent surgery and pathological examination revealing a 1.0 x 1.2 cm parathyroid adenoma with areas of necrosis with hemosiderinladen macrophages. In conclusion, we describe a case of spontaneous short-term remission of PHPT due to infarction of parathyroid adenoma.

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Authors and Affiliations

  1. Department of Endocrinology and Metabolism, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy

    F. Cetani MD, PhD, E. Ambrogini, P. Vitti, A. Pinchera & C. Marcocci

  2. Department of Oncology, University of Pisa, Pisa, Italy

    P. Faviana

  3. Department of Surgery, University of Pisa, Pisa, Italy

    P. Berti

Authors
  1. F. Cetani MD, PhD
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  2. E. Ambrogini
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  3. P. Faviana
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  4. P. Vitti
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  5. P. Berti
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  6. A. Pinchera
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  7. C. Marcocci
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Correspondence to F. Cetani MD, PhD.

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Cetani, F., Ambrogini, E., Faviana, P. et al. Spontaneous short-term remission of primary hyperparathyroidism from infarction of a parathyroid adenoma. J Endocrinol Invest 27, 687–690 (2004). https://doi.org/10.1007/BF03347505

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  • DOI: https://doi.org/10.1007/BF03347505

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