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Prostatic neuroendocrine tumor in multiple endocrine neoplasia Type 2B

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Abstract

We report the unusual occurrence of a neuroendocrine prostatic tumor in two young males with multiple endocrine neoplasia (MEN) 2B. Immunohistochemistry of the tumor markers may help differentiate a primary neuroendocrine prostate tumor from the metastasis of a medullary thyroid carcinoma of poor prognosis. MEN 2B hallmarks (i.e. plasma thyrocalcitonin and urinary metanephrines) may be systematically investigated in neuroendocrine tumors of the prostate, and conversely prostate examination may be performed in the periodic screening of MEN 2B male patients.

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Authors and Affiliations

  1. Department of Endocrinology, Hospital CHU, Côte de Nacre, 14033, Caen, France

    B. Goulet-Salmon, E. Berthe, J. Mahoudeau & Y. Reznik

  2. Department of Endocrinology, Hospital Pitié-Salpetrière, Paris, France

    S. Franc

  3. Department of Pathology, France

    S. Chanel & F. Galateau-Salle

  4. Department of Genetic and Reproduction, Hospital CHU, Caen, France

    M. Kottler

Authors
  1. B. Goulet-Salmon
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  2. E. Berthe
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  3. S. Franc
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  4. S. Chanel
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  5. F. Galateau-Salle
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  6. M. Kottler
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  7. J. Mahoudeau
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  8. Y. Reznik
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Goulet-Salmon, B., Berthe, E., Franc, S. et al. Prostatic neuroendocrine tumor in multiple endocrine neoplasia Type 2B. J Endocrinol Invest 27, 570–573 (2004). https://doi.org/10.1007/BF03347481

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  • DOI: https://doi.org/10.1007/BF03347481

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