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Insulin resistance in children with Helicobacter pylori infection

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Abstract

We aimed at investigating insulin resistance in children with Helicobacter pylori (H. pylori) infection. Fasting serum insulin and glucose levels were determined in 31 children with H. pylori (+) (H. pylori-infected group, 20 girls and 11 boys, median age 12 yr, range 6–17) and 29 H. pylori (−) (control group, 18 girls and 11 boys, median age 13 yr, range 5–16). Insulin resistance was assessed using homeostasis model assessment of insulin resistance (HOMA-IR) score. Fasting serum glucose levels did not differ significantly between H. pylori (+) and (−) children. Both HOMA-IR score and serum insulin levels were significantly higher in H. pylori-infected compared to control children. The findings of the present study suggested that there is a certain relation between H. pylori infection and insulin resistance in children.

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Authors and Affiliations

  1. Central Laboratory. Clinical Biochemistry Unit, Akdeniz University, Medical Faculty, 07070, Antalya, Turkey

    S. Ozdem MD

  2. Division of Pediatric Gastroenterology, Hepatology and Nutrition; Department of Pediatrics, Medical Faculty, Akdeniz University, Antalya, Turkey

    M. Akcam, A. Yilmaz & R. Artan

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Ozdem, S., Akcam, M., Yilmaz, A. et al. Insulin resistance in children with Helicobacter pylori infection. J Endocrinol Invest 30, 236–240 (2007). https://doi.org/10.1007/BF03347431

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